| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20010952m |
| Family | GT47 |
| Protein Properties | Length: 729 Molecular Weight: 78352.3 Isoelectric Point: 8.2589 |
| Chromosome | Chromosome/Scaffold: 42 Start: 293364 End: 296121 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 230 | 532 | 3.9e-39 |
| GPRIYVYELPPEMNTFQNLDRLDRPLMYLIWQRLLSAGLRVADAASADFFLVPIRVRMAYDSDRVIQAVSYIRSVWPYWNATRGGGRHIFVHTGDWGRDE LSEDAQLLTRNATWLTHWGLARDHEFAGWRQSHRPGKDVVLPLMLAASLLSTYQLPRASPLHPAGPRPERTTTLFFAGRICGSRATPSLNGTYPNCPNVL GSEDAYSAATRQRAYFYHHGRANWKLVTASRAPAAEMATAKFCLAPSGGGQGKRSVLAPLMGCVPVPVTDGLMQPFEPELRWERFAVGVRERDLPVMHEL LDR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 729 Download |
| MQLLRCPDKA RRGVMSLDMA CDVRCFKPIS YLFITLTLVN VASLAKEKLA SARETSGGSK 60 ANNITDVESN SRRSNSERLT TGNVIDNPPR RSTCPGHCTK YGTCYEELGR CDCPPGRVGE 120 DCASQLPASE LTQLCAANGH TNATCAVELE LALCLNACNF RGRCVGGVCV CQPGYFGADC 180 SLSLAMQPPG ADGGAAAAAA AAAAAAGGGI AGGVLMELLA GQNYTPRPSG PRIYVYELPP 240 EMNTFQNLDR LDRPLMYLIW QRLLSAGLRV ADAASADFFL VPIRVRMAYD SDRVIQAVSY 300 IRSVWPYWNA TRGGGRHIFV HTGDWGRDEL SEDAQLLTRN ATWLTHWGLA RDHEFAGWRQ 360 SHRPGKDVVL PLMLAASLLS TYQLPRASPL HPAGPRPERT TTLFFAGRIC GSRATPSLNG 420 TYPNCPNVLG SEDAYSAATR QRAYFYHHGR ANWKLVTASR APAAEMATAK FCLAPSGGGQ 480 GKRSVLAPLM GCVPVPVTDG LMQPFEPELR WERFAVGVRE RDLPVMHELL DRLMPEQVAG 540 FQAELTCAAQ HLFWSSLYGS VFGEDGAYDA FETLVQVLRM RATYPNVAPE EYEYVDAAFA 600 AFMECREPPP PAAAAVAAAA EAGKSGGLQR TLAASSQWLR PLPQRRRGPA PASPPPPSPS 660 ATATLTAAAT ATTATAASRQ ALCSHSALPT PGAQSCGRCV RRRGRLLNPG GTICCNTREL 720 AKCPRLWD* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.004 | 156 | 180 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 6.0e-31 | 227 | 532 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 94 | 605 | 5 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702517.1 | 0 | 90 | 580 | 6 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 41 | 606 | 19 | 554 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 103 | 622 | 3 | 488 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703125.1 | 0 | 89 | 614 | 62 | 516 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4k0v_A | 0.01 | 98 | 182 | 205 | 291 | A Chain A, Structural Basis For Angiopoietin-1 Mediated Signaling Initiation |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD838948 | 281 | 305 | 575 | 0 |
| BU654073 | 258 | 112 | 363 | 2.00386e-43 |
| AV627636 | 198 | 135 | 331 | 3e-38 |
| FD821819 | 124 | 482 | 605 | 9e-33 |
| BI722824 | 193 | 91 | 282 | 4e-32 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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