| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20011523m |
| Family | GT47 |
| Protein Properties | Length: 402 Molecular Weight: 45047.2 Isoelectric Point: 8.7051 |
| Chromosome | Chromosome/Scaffold: 5 Start: 2010413 End: 2014309 |
| Description | FRA8 homolog |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 1 | 261 | 2.29995e-41 |
| MQRLLSSGVRTADGDAADFFFIPLVMRTKGQSANHLTAVVSYIQQHWPWWGRYGGGHRHLLVVPADLGRRMLPEELLKLVENVTFLTHWGSHTNHSEGAW VESHRPGKDIVVPPLHNADEPIVFSPLHTLHSKRRRQRTSGLFFSGRICSDGSEPHRGRCRTNSQGNVRHKVLKHHWNRTTWTLTTRAKAYASALSSHTF CLSPGGGGYGRRSVQAAVMGCVPVLIGDGLHQPFEPELDWSQFSMSVPEQDIPHLHTILES | |||
| Full Sequence |
|---|
| Protein Sequence Length: 402 Download |
| MQRLLSSGVR TADGDAADFF FIPLVMRTKG QSANHLTAVV SYIQQHWPWW GRYGGGHRHL 60 LVVPADLGRR MLPEELLKLV ENVTFLTHWG SHTNHSEGAW VESHRPGKDI VVPPLHNADE 120 PIVFSPLHTL HSKRRRQRTS GLFFSGRICS DGSEPHRGRC RTNSQGNVRH KVLKHHWNRT 180 TWTLTTRAKA YASALSSHTF CLSPGGGGYG RRSVQAAVMG CVPVLIGDGL HQPFEPELDW 240 SQFSMSVPEQ DIPHLHTILE SMNSSTIAAM QEQLRCAAQH LYYSTTFGEV MGEDGRYDAF 300 ETLMEVLRMR RDHPSLDPSE YARTDSRFAD FINCKLEPTG GPVSLCTQNR MIMAADGRNL 360 RPCRLEFPGL SMRSMHMFYS WPGGAVCGSN RSVAACPRSW V* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-36 | 1 | 262 | 272 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 1 | 334 | 149 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702517.1 | 0 | 1 | 309 | 148 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 2 | 399 | 209 | 615 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 2 | 339 | 133 | 476 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703125.1 | 0 | 2 | 340 | 209 | 512 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD838948 | 275 | 45 | 304 | 0 |
| FD821819 | 198 | 211 | 400 | 6.02558e-44 |
| BI532593 | 153 | 184 | 335 | 1e-33 |
| BI532624 | 155 | 182 | 335 | 2e-32 |
| AV627636 | 72 | 1 | 72 | 7e-28 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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