| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20011529m |
| Family | GT47 |
| Protein Properties | Length: 1123 Molecular Weight: 124455 Isoelectric Point: 8.9966 |
| Chromosome | Chromosome/Scaffold: 5 Start: 2017715 End: 2032499 |
| Description | tetratricopeptide repeat (TPR)-containing protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 563 | 889 | 7.4e-33 |
| IKIYVYELPPNMTSWPCADLQQFLTPLPRAPSGPPAPSLSPYPTRRQPPKCPQPYIGFFSRFNIRRLDRPLHLLFWQRLMSAGIRTVDGDEADYYFIPVN TRTELAPGMVEWVLSYIRRTYPWWSKDNGNRHLIIHTGDMGIADLPADMRSRLKSAFSNITWLTHWGIYQYHPVAKWYPAHRPGKDVVLPVMVTTQGFHL SPLNPRVEARARRRNQTMARSGTFFFAGRICGDRKPPDPATGDCSRTRPDYSGGVRQLDISSHKFCLAPLGGGHGKRQVLVSLMGCVPVLIGNGVLQPFE PEIDWSRFSVSVPEADIPDLPRILANI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1123 Download |
| MTPMCHPHLR GALSAKRLQQ ACRPCFVASR VAPRLPGLLV VARSSKPASA SKPQYQPTSA 60 RDAIETATRV FKEQQDVDEA VRLYRLGLDM KPNEDEARAA LYNLGCALAK QKKWAEASDS 120 IVKAINDYKL KLTVALKDED LKQLRERREW IDALTQVKGG ISRSTKVDLR TEAKAPFRLP 180 RIILFGGLLG SAAIGLVIIV FRLVKALQGG PEAPDLNESL TNLGVNSVAV AVLSYLLYRD 240 VSQKQEAVRI TTREELMGRL QIDLGNDRVL PLLKFRGQVR PVIVAGTRSF VERAIKEADS 300 QYINLRDRAV SVIPVIFESA PVGDVDPEIK LRALRKEFAK EARGFDESAA AAKKAAAEAA 360 EARAARSKAT VLGGLMDADK RWRLEPYAVD EWKAWILEQK EFAGLSPREP NCYIQVQLDG 420 TVRSSGPGTP PWRQLVEDLP LLSDFRTRLM DGVGPQDCLP GCHVKGVCNE ELATCFCPRH 480 FTGPSCSDVA SNIKDICATY GFTLSQCRKA SPCFNSCNER GRCVAGICHC QPGYWGMDCA 540 ISWGPNGKMQ LLDGLYKPRN GSIKIYVYEL PPNMTSWPCA DLQQFLTPLP RAPSGPPAPS 600 LSPYPTRRQP PKCPQPYIGF FSRFNIRRLD RPLHLLFWQR LMSAGIRTVD GDEADYYFIP 660 VNTRTELAPG MVEWVLSYIR RTYPWWSKDN GNRHLIIHTG DMGIADLPAD MRSRLKSAFS 720 NITWLTHWGI YQYHPVAKWY PAHRPGKDVV LPVMVTTQGF HLSPLNPRVE ARARRRNQTM 780 ARSGTFFFAG RICGDRKPPD PATGDCSRTR PDYSGGVRQL DISSHKFCLA PLGGGHGKRQ 840 VLVSLMGCVP VLIGNGVLQP FEPEIDWSRF SVSVPEADIP DLPRILANIS DQRVADMQAR 900 EKRGGRGKGE KGRGNEGRES GCALLHVLRF WFPLGFCGGL GVLKAGGEGG WESCARTCTH 960 TRGPSVCVCA AYDTGMQPGH KRLRCAAQHM FYSSTLGAIL GEDGRYGGWG IRWGLRVCGG 1020 GADAFETIIE ILRVRKAHPD VPPEQYIHVD ERFRKFVDCD LGGPDQILCN QGHERQYKAT 1080 PTCGECHQHV AAQRTGSTFY SWAGGMVCCS ELDMTKCPRV WP* 1140 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00189 | TPR | 0.0003 | 70 | 126 | 57 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| cd00189 | TPR | 0.0003 | 70 | 126 | 57 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| pfam11998 | DUF3493 | 1.0e-18 | 161 | 242 | 82 | + Protein of unknown function (DUF3493). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 79 to 331 amino acids in length. | ||
| pfam03016 | Exostosin | 4.0e-30 | 637 | 889 | 275 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| PLN03098 | LPA1 | 2.0e-59 | 56 | 449 | 399 | + LOW PSII ACCUMULATION1; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABL73934.1 | 0 | 12 | 457 | 6 | 449 | photosystem-II repair protein [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 458 | 900 | 73 | 492 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 6e-40 | 981 | 1118 | 491 | 613 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 475 | 898 | 10 | 408 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0.000000000001 | 981 | 1059 | 409 | 471 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2ygq_A | 0.00004 | 457 | 545 | 150 | 248 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 2wqh_A | 0.001 | 57 | 128 | 5 | 73 | A Chain A, Crystal Structure Of Ctpr3y3 |
| PDB | 2wqh_A | 0.004 | 71 | 128 | 53 | 107 | A Chain A, Crystal Structure Of Ctpr3y3 |
| PDB | 1na3_B | 0.002 | 57 | 125 | 5 | 70 | A Chain A, Design Of Stable Alpha-Helical Arrays From An Idealized Tpr Motif |
