| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20011939m |
| Family | GT57 |
| Protein Properties | Length: 528 Molecular Weight: 57703.2 Isoelectric Point: 9.1256 |
| Chromosome | Chromosome/Scaffold: 46 Start: 560339 End: 565815 |
| Description | ALG6, ALG8 glycosyltransferase family |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT57 | 12 | 511 | 0 |
| ATACKLLLVPTYRSTDFEVHRNWLAITHNLPISKWYVEATSEWTLDYPPFFAWFEWLLSQFALFVDPAMLVVQNLEYASERTVLFQRASVIVTDLVLLAA SYALARWEPRNSSGSDNVNMRRGAVLFFLVSCNAGLMLVDHVHFQYNGVMMGVLLWSLYAACRGRMLASGLLFAALLNMKHLFLYAAPAYFVVLLRHYCC EGTAIGGEERGAAGFGRIALRLAVLGSGVLAIFGASFGPFIVMGQMPQVLRRLFPFGRGLMHAYWAANAWAPYAAADKLLAVGLPRIAPWLGLDLERMGL RIQRGAANMAARTRSLPQVTPAATALAVLVGLLPCLAALWAGDGRPGYVRRNIFRAVSYSFLCGFVFGYHVHEKAVLVALLPLAVDAVVSPVAARRFLLL ASAGHYGLLPLLFRPQEYGAKVLLVLSYFVVSAAALCGLHAEVQPSAGPPVKAYMVGFLLVELYVSVVHDAVPFLRRNLPFAPLMLTSVYCSVAVLAVWV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 528 Download |
| MVPFCLQIAV IATACKLLLV PTYRSTDFEV HRNWLAITHN LPISKWYVEA TSEWTLDYPP 60 FFAWFEWLLS QFALFVDPAM LVVQNLEYAS ERTVLFQRAS VIVTDLVLLA ASYALARWEP 120 RNSSGSDNVN MRRGAVLFFL VSCNAGLMLV DHVHFQYNGV MMGVLLWSLY AACRGRMLAS 180 GLLFAALLNM KHLFLYAAPA YFVVLLRHYC CEGTAIGGEE RGAAGFGRIA LRLAVLGSGV 240 LAIFGASFGP FIVMGQMPQV LRRLFPFGRG LMHAYWAANA WAPYAAADKL LAVGLPRIAP 300 WLGLDLERMG LRIQRGAANM AARTRSLPQV TPAATALAVL VGLLPCLAAL WAGDGRPGYV 360 RRNIFRAVSY SFLCGFVFGY HVHEKAVLVA LLPLAVDAVV SPVAARRFLL LASAGHYGLL 420 PLLFRPQEYG AKVLLVLSYF VVSAAALCGL HAEVQPSAGP PVKAYMVGFL LVELYVSVVH 480 DAVPFLRRNL PFAPLMLTSV YCSVAVLAVW VDAAIEWARD VAAAAGW* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03155 | Alg6_Alg8 | 4.0e-12 | 372 | 511 | 145 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| pfam03155 | Alg6_Alg8 | 5.0e-74 | 10 | 304 | 310 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAH90105.1 | 0 | 8 | 524 | 22 | 526 | alg8-prov protein [Xenopus (Silurana) tropicalis] |
| RefSeq | NP_001076820.1 | 0 | 8 | 524 | 32 | 536 | dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [Xenopus (Silurana) tropicalis] |
| RefSeq | NP_001084808.1 | 0 | 6 | 524 | 33 | 539 | asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog [Xenopus laevis] |
| RefSeq | XP_001377643.1 | 0 | 6 | 516 | 19 | 516 | PREDICTED: similar to Asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase) [Monodelphis domestica] |
| RefSeq | XP_001696729.1 | 0 | 12 | 510 | 1 | 518 | glycosyl transferase, type ALG6, ALG8 [Chlamydomonas reinhardtii] |
