| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20012263m |
| Family | GH47 |
| Protein Properties | Length: 853 Molecular Weight: 94758.5 Isoelectric Point: 4.9848 |
| Chromosome | Chromosome/Scaffold: 47 Start: 615958 End: 622844 |
| Description | alpha-mannosidase 3 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH47 | 43 | 516 | 0 |
| WTWKGYRQYAWGHDELNAGSRTSREWFALGLTIVDSLDTLQILGLLEEYAEARFWVANHLNFNQGEVSVFETTIRILGGLVAAFYHSGGDELFLLKAVEF AESVHDTEEPRGKFGIGSTCLAEVATVSMEFSAVSRLSGRPEFRDTAMIPWQKLTSMQDLDGLYCTFLNGDSLGCSGNHYTMGASADSAYEYMLKQWIMN KNDSMCIDMYKKAIGGMRKHMLTQLWMGEDIGDVWIVAENDGGRTRSNILEHLTCFLPGTIALGHMYGINTASSPDEDDDLTVAVKLMKACYELYHQTAT GVAFDSVLLVPRYSPEPVVDKGIGQFQTGTTFTAGSTATGNGNQQESSGKGRILLQDGGSAGKTKYAFAPRSRENFLRPEVAESLFYLWRATGDPIYREW GWNMFRAYERWCRVSTGGYQVLNNVDTVPPSVGNKMESFWMAETMKYFYLLFSDDPDEIPLDEFVFNTEAHPLA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 853 Download |
| MLTSQKYIQS GICDGNYTCG VDGLGCITDA LLRKEKVREA ARWTWKGYRQ YAWGHDELNA 60 GSRTSREWFA LGLTIVDSLD TLQILGLLEE YAEARFWVAN HLNFNQGEVS VFETTIRILG 120 GLVAAFYHSG GDELFLLKAV EFAESVHDTE EPRGKFGIGS TCLAEVATVS MEFSAVSRLS 180 GRPEFRDTAM IPWQKLTSMQ DLDGLYCTFL NGDSLGCSGN HYTMGASADS AYEYMLKQWI 240 MNKNDSMCID MYKKAIGGMR KHMLTQLWMG EDIGDVWIVA ENDGGRTRSN ILEHLTCFLP 300 GTIALGHMYG INTASSPDED DDLTVAVKLM KACYELYHQT ATGVAFDSVL LVPRYSPEPV 360 VDKGIGQFQT GTTFTAGSTA TGNGNQQESS GKGRILLQDG GSAGKTKYAF APRSRENFLR 420 PEVAESLFYL WRATGDPIYR EWGWNMFRAY ERWCRVSTGG YQVLNNVDTV PPSVGNKMES 480 FWMAETMKYF YLLFSDDPDE IPLDEFVFNT EAHPLAIWGT ETDLTLREVL ANAHGRLEAS 540 GVNALGKSAQ YYQSNLMGMT AAERHKKFVN DYLTYYACGR DEPSTKNDAA RIRTDADALR 600 EHHRFIRSDA DNESSSWEAR LAKRYYDRLF KEYAIVDLTY YKQSKLGMRW RTQKEVVSGK 660 GQFVCGAKGC DAGEGLCSYE VNFAYQEAGE RKQALVKLRL CPACAFKLNY RKEKQLQKAA 720 DAAAARKRKR EQELEERMPN DPLVQEALEY VQRYAHGGSD EAGPFNPEAG IGTADFERAT 780 GDVAPPPAAT AARAGGSGVA IDALGGTGTE GAQRAPAVIT LPADNSVWEL KPAQETVNVE 840 EEMDAYFEGL FL* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam09725 | Fra10Ac1 | 5.0e-58 | 593 | 710 | 118 | + Folate-sensitive fragile site protein Fra10Ac1. This entry represents the full-length proteins in which, in higher eukaryotes, the nested domain EDSLL lies. Fra10Ac1 is a highly conserved protein, of unknown function that is nuclear and highly expressed in brain. | ||
| PTZ00470 | PTZ00470 | 3.0e-126 | 33 | 517 | 508 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 6.0e-145 | 40 | 515 | 501 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1FMI | 0 | 33 | 518 | 10 | 457 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1FO2 | 0 | 33 | 518 | 10 | 457 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| RefSeq | XP_001374485.1 | 0 | 33 | 519 | 260 | 708 | PREDICTED: similar to Mannosidase, alpha, class 1B, member 1 [Monodelphis domestica] |
| RefSeq | XP_001700094.1 | 0 | 10 | 533 | 122 | 655 | alpha-1,2-mannosidase [Chlamydomonas reinhardtii] |
| RefSeq | XP_537786.2 | 0 | 33 | 524 | 207 | 660 | PREDICTED: similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific processing alpha-mannosidase) [Canis familiaris] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1fmi_A | 0 | 33 | 518 | 10 | 457 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 33 | 518 | 10 | 457 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 33 | 518 | 10 | 457 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 33 | 518 | 88 | 535 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| PDB | 1nxc_A | 0 | 29 | 517 | 14 | 465 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO455472 | 304 | 550 | 853 | 0 |
| AJ778611 | 162 | 550 | 711 | 0 |
| BP919771 | 164 | 549 | 711 | 0 |
| FK011960 | 162 | 550 | 711 | 0 |
| ES256837 | 162 | 550 | 711 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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