| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20012273m |
| Family | GT2 |
| Protein Properties | Length: 340 Molecular Weight: 37535.4 Isoelectric Point: 8.9904 |
| Chromosome | Chromosome/Scaffold: 32 Start: 225692 End: 229232 |
| Description | Nucleotide-diphospho-sugar transferases superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT2 | 63 | 179 | 8.1e-35 |
| SCIIPAYNEEDRLPSTLDEALAYLQRRRDRQGPQFTYELIIVDDGSKDGTARVAQSYVRKYGMDTVRLLRVSANRGKGHAVKRGMLAARGEYCLLMDADG ATRFSDLEKLEAELDKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 340 Download |
| MFYDILLWLG LLAAGYTLGK VINLVTALSK EFTEPISCTL EDPDSTSPVA CPSIFDAPTK 60 ALSCIIPAYN EEDRLPSTLD EALAYLQRRR DRQGPQFTYE LIIVDDGSKD GTARVAQSYV 120 RKYGMDTVRL LRVSANRGKG HAVKRGMLAA RGEYCLLMDA DGATRFSDLE KLEAELDKIL 180 QPSFGRSSAA SAATGDTQGP LGVAYGSRAH LHKDAIVKRS RLRNFLTRGF HMLVYFVAGG 240 RIRDTQCGFK LFTRRSAAIL FSNMRLQRWC FDVELLYLAE QLQIPVCEVF VNWTEIPGSK 300 IRFTSILLMA LELLIIKARP PATSGLLSAT RGLTHALGT* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06442 | DPM1_like | 7.0e-26 | 65 | 289 | 226 | + DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily. | ||
| pfam00535 | Glycos_transf_2 | 1.0e-26 | 63 | 261 | 199 | + Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. | ||
| cd04179 | DPM_DPG-synthase_like | 1.0e-56 | 65 | 279 | 215 | + DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily. | ||
| PTZ00260 | PTZ00260 | 1.0e-102 | 62 | 319 | 262 | + dolichyl-phosphate beta-glucosyltransferase; Provisional | ||
| cd04188 | DPG_synthase | 1.0e-108 | 65 | 300 | 236 | + DPG_synthase is involved in protein N-linked glycosylation. UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAO18453.1 | 0 | 29 | 317 | 81 | 368 | putative dolichyl-phosphate beta-glucosyltransferase [Oryza sativa Japonica Group] |
| GenBank | EEC76428.1 | 0 | 29 | 317 | 53 | 340 | hypothetical protein OsI_14108 [Oryza sativa Indica Group] |
| RefSeq | NP_001051729.1 | 0 | 29 | 317 | 53 | 340 | Os03g0821800 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001140935.1 | 0 | 40 | 317 | 62 | 338 | hypothetical protein LOC100273013 [Zea mays] |
| RefSeq | XP_001698146.1 | 0 | 1 | 339 | 1 | 372 | dolichol-phosphate glucosyltransferase [Chlamydomonas reinhardtii] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ckv_A | 0.0002 | 60 | 161 | 48 | 141 | A Chain A, Recombinant Human Acetylcholinesterase |
| PDB | 3ckq_A | 0.0002 | 60 | 161 | 48 | 141 | A Chain A, Recombinant Human Acetylcholinesterase |
| PDB | 3cko_A | 0.0002 | 60 | 161 | 48 | 141 | A Chain A, Recombinant Human Acetylcholinesterase |
| PDB | 3ckn_A | 0.0002 | 60 | 161 | 48 | 141 | A Chain A, Recombinant Human Acetylcholinesterase |
| PDB | 3ckj_A | 0.0002 | 60 | 161 | 48 | 141 | A Chain A, Crystal Structure Of A Mycobacterial Protein |
