| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20012823m |
| Family | GT47 |
| Protein Properties | Length: 617 Molecular Weight: 69550.6 Isoelectric Point: 8.7313 |
| Chromosome | Chromosome/Scaffold: 3 Start: 3995211 End: 4003691 |
| Description | FRA8 homolog |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 227 | 484 | 2.5e-32 |
| IWKRIISSGHRTLNGGEADYFYIPVDFRHMFSEAFEVLEYVQATWPFWNATGGDLGGCEGKQLMLLRNLTSAAIWLTPWGLTRKHPRVWWPGCHRPGHDI VIPVLAQANNMIMTPLNPKVKPLPRNTTFYFAGKICGDNKDPKEDTSSWPICQTPRNPLYSAGVRQLVYFYHSKRDGFVVRPRSSSYVRDMSTSKFCLAP TGGGHGKRQVLVGRYGCIPVPITDYVLQPFEPELDWPAFSVTVKEEDVPNLHTILAAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 617 Download |
| MISLQHHTTW GIQLLAVMSI AVLAPRPGLA LPCAANCTKY GTCNLELGRY GSWRTSVTMY 60 GFPVARTASS YFPGARSRQP VRNIVRKCGF LGFFTVEDCL AEYPLRCMNA CNKRGRCING 120 WCHCYEGYYG ADCSLSLDAN GSEGQNSSLD WDSYPHLVAL RSTFMSCLRS SPRSKDWNSF 180 EGEVGKGLRK GGGWGKRRTS ANVRMAVLEV RGSKNLEKFD RPLYAHIWKR IISSGHRTLN 240 GGEADYFYIP VDFRHMFSEA FEVLEYVQAT WPFWNATGGD LGGCEGKQLM LLRNLTSAAI 300 WLTPWGLTRK HPRVWWPGCH RPGHDIVIPV LAQANNMIMT PLNPKVKPLP RNTTFYFAGK 360 ICGDNKDPKE DTSSWPICQT PRNPLYSAGV RQLVYFYHSK RDGFVVRPRS SSYVRDMSTS 420 KFCLAPTGGG HGKRQVLVGR YGCIPVPITD YVLQPFEPEL DWPAFSVTVK EEDVPNLHTI 480 LAAINDTKLA EMQRALACAA KHLWYSSMWG AIFGEDSRYD AFATLMEILR VRSLYPHAQP 540 HEYRSLDERF RRFANCELDN EPPQRFHLCT YGLDPGLEAY APTPYCDWRP YMKYGIPGGA 600 ICEGAPNVAQ CPRPWQ* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-29 | 223 | 484 | 286 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001690974.1 | 0 | 292 | 616 | 24 | 341 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693540.1 | 0 | 29 | 615 | 1 | 509 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702214.1 | 0 | 100 | 616 | 1 | 393 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 33 | 574 | 73 | 569 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 83 | 576 | 29 | 490 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
