| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20013770m |
| Family | GT47 |
| Protein Properties | Length: 707 Molecular Weight: 79417.2 Isoelectric Point: 6.6747 |
| Chromosome | Chromosome/Scaffold: 54 Start: 230442 End: 241709 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 295 | 655 | 4.06377e-44 |
| HAAIKIYVYDLPSIVLHRREFQDQWSYIDLMYNAELEFTERLLGDWSVRTENPWEAALFYVPTFTYWFTGNVGHPTFIFQHVVHHLQHLAPFFNLTGGRN HVMWATNDRGACKLQMSQLELQHPIKMVHFGQAPRHAYLQKAHMMGSGHGIDTLGGVASLLGALPHPGHRFEEFPEFTAADILEEHEICLRPEKDVVTPN VLHQGWVEPGAYRQVWDVKFVDGERVVTRQQDDLEKRTYTLFFGGYTKSIMAYSQGVRQALRSMFGPGGKYDPNGPNARSDFLVTDPRHDAIDLMARSKF CLAPMGAGWGIRLAEAMVRGCVPVVIQDHVYQPLWDVVPFEEFSLRFSRRDVADLVDHLDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 707 Download |
| MRAMYCCFFL SAKLVLFGLA DMATATVKLD NATARSGWQA PPAHKSCFPH VTRAMKTALC 60 PTTETAGETV GETVGEAVGE TVGEAQGGEK AMERVKVLSG RQLSEHPYSC PSYLKYEGSG 120 HVPQPPCFYD ILLNNNLLCY RYKGVPESQQ LSDSPSLDDP DVEWLHVRGY PTFQELQAMP 180 SPKEVKMPDG IYRPLKECPG RCSDRGWCQS LGGNVLMERH EDPEERWCHC HSFFRGKTCE 240 IADPLHCYRN CSGVGTCLNG WCHCEPGYWG HGCTRTKAYG SKVGTCGLVG WRPNHAAIKI 300 YVYDLPSIVL HRREFQDQWS YIDLMYNAEL EFTERLLGDW SVRTENPWEA ALFYVPTFTY 360 WFTGNVGHPT FIFQHVVHHL QHLAPFFNLT GGRNHVMWAT NDRGACKLQM SQLELQHPIK 420 MVHFGQAPRH AYLQKAHMMG SGHGIDTLGG VASLLGALPH PGHRFEEFPE FTAADILEEH 480 EICLRPEKDV VTPNVLHQGW VEPGAYRQVW DVKFVDGERV VTRQQDDLEK RTYTLFFGGY 540 TKSIMAYSQG VRQALRSMFG PGGKYDPNGP NARSDFLVTD PRHDAIDLMA RSKFCLAPMG 600 AGWGIRLAEA MVRGCVPVVI QDHVYQPLWD VVPFEEFSLR FSRRDVADLV DHLDDVTSEQ 660 LARLQGGVER YHRWEEWGMG EVGGYDGGHL QAGRACRGGM CSGRGL* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam13692 | Glyco_trans_1_4 | 0.001 | 563 | 619 | 59 | + Glycosyl transferases group 1. | ||
| pfam03016 | Exostosin | 4.0e-23 | 295 | 644 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693329.1 | 0 | 194 | 677 | 138 | 571 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694919.1 | 0 | 135 | 684 | 104 | 652 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 101 | 678 | 90 | 657 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 101 | 677 | 108 | 676 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699926.1 | 0 | 135 | 684 | 262 | 760 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
