| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20013934m |
| Family | AA3 |
| Protein Properties | Length: 611 Molecular Weight: 65006 Isoelectric Point: 8.6656 |
| Chromosome | Chromosome/Scaffold: 6 Start: 2810841 End: 2816740 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 41 | 600 | 0 |
| GSEKFDYILVGGGTAGCVLANKLSANGSKKVLVLEAGPTGDAMEVAVPAGIARLFAHPVFDWGMSSLTQQQLVAREIYLARGRLLGGSSGTNATLYHRGT PADYDSWGLEGWTSKDLLDWFVKAECYGDGPRAFHGQSGSMNVEQPRYQNVLHDEFFRAAAAAGLPANEDFNDWSRPQEGYGEFQVAQKNGERADTYRTY LKPAMGRDNLKVMTGARTTKVHIEKSSTGPRARGVEYATQQFGERYTAELTPGGEVLMCTGAVHTPHLLMLSGIGPAPTLLEHGLDVISSLPGVGANLQD HPAAVLAVRAKPEFEGLSVTSEIYDSKCNIRLGAVMKYLFGRRGPLATTGCDHGAFVRTSASHSQPDLQMRFVPGCALDPDGVKSYIVFGELKKQGRAWP GGITLQLLGIRAKSRGSIGLKAADPFINPAININYFSDPEDLATLKNGVRIAREIVAQEPLRKYLLEETFPGERANTDKDIEEYVRRTVHSGNALVGTCA MGTTPASGAVVSSADLKVFGVDGLRVVDASVLPRIPGGQTGAATVMVAERAAAMLLGQAT | |||
| Full Sequence |
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| Protein Sequence Length: 611 Download |
| MLLGQRPFGA PAKGAMPCWK AARHGGVARR PVAVKAAASV GSEKFDYILV GGGTAGCVLA 60 NKLSANGSKK VLVLEAGPTG DAMEVAVPAG IARLFAHPVF DWGMSSLTQQ QLVAREIYLA 120 RGRLLGGSSG TNATLYHRGT PADYDSWGLE GWTSKDLLDW FVKAECYGDG PRAFHGQSGS 180 MNVEQPRYQN VLHDEFFRAA AAAGLPANED FNDWSRPQEG YGEFQVAQKN GERADTYRTY 240 LKPAMGRDNL KVMTGARTTK VHIEKSSTGP RARGVEYATQ QFGERYTAEL TPGGEVLMCT 300 GAVHTPHLLM LSGIGPAPTL LEHGLDVISS LPGVGANLQD HPAAVLAVRA KPEFEGLSVT 360 SEIYDSKCNI RLGAVMKYLF GRRGPLATTG CDHGAFVRTS ASHSQPDLQM RFVPGCALDP 420 DGVKSYIVFG ELKKQGRAWP GGITLQLLGI RAKSRGSIGL KAADPFINPA ININYFSDPE 480 DLATLKNGVR IAREIVAQEP LRKYLLEETF PGERANTDKD IEEYVRRTVH SGNALVGTCA 540 MGTTPASGAV VSSADLKVFG VDGLRVVDAS VLPRIPGGQT GAATVMVAER AAAMLLGQAT 600 ITSRREPAAV * 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03970 | Rv0697 | 8.0e-14 | 436 | 576 | 142 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR03970 | Rv0697 | 1.0e-39 | 46 | 353 | 321 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 4.0e-94 | 46 | 578 | 539 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 5.0e-112 | 42 | 580 | 547 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PRK02106 | PRK02106 | 4.0e-126 | 42 | 578 | 548 | + choline dehydrogenase; Validated | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX23098.1 | 0 | 40 | 602 | 8 | 550 | alcohol dehydrogenase [Alcanivorax borkumensis SK2] |
| RefSeq | XP_001703004.1 | 0 | 1 | 610 | 1 | 611 | predicted protein [Chlamydomonas reinhardtii] |
| RefSeq | XP_002178042.1 | 0 | 45 | 595 | 1 | 539 | predicted protein [Phaeodactylum tricornutum CCAP 1055/1] |
| RefSeq | YP_691922.1 | 0 | 43 | 602 | 4 | 543 | alcohol degydrogenase [Alcanivorax borkumensis SK2] |
| RefSeq | ZP_05043291.1 | 0 | 44 | 598 | 2 | 531 | GMC oxidoreductase family [Alcanivorax sp. DG881] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fim_B | 0 | 44 | 595 | 2 | 562 | B Chain B, Crystal Structure Of Aryl-Alcohol-Oxidase From Pleurotus Eryingii |
| PDB | 3nne_H | 0 | 34 | 595 | 3 | 526 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 3nne_G | 0 | 34 | 595 | 3 | 526 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 3nne_F | 0 | 34 | 595 | 3 | 526 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 3nne_E | 0 | 34 | 595 | 3 | 526 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD836615 | 268 | 106 | 373 | 0 |
| FD835421 | 246 | 187 | 432 | 0 |
| FD820451 | 231 | 255 | 485 | 0 |
| BI724929 | 218 | 262 | 479 | 0 |
| FD806224 | 217 | 1 | 217 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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