| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20014584m |
| Family | GT4 |
| Protein Properties | Length: 447 Molecular Weight: 48989.8 Isoelectric Point: 9.1553 |
| Chromosome | Chromosome/Scaffold: 27 Start: 1304560 End: 1306363 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT4 | 233 | 409 | 4.2e-33 |
| GGTTFLSINRFERKKGIRLALEALCELRERQGTSRTKSTSTMATVPSATEGSAAAPPPRARLVVAGGYDPRLPENVEYLKELREAARQMGLLEVVRFMPS FTDRQRTLLLAACRAVLYTPQHEHFGIVPLEAMAAGRPVVACDSGGPTESVTHGAVGFLCAPAAAAFASAMAELMDA | |||
| Full Sequence |
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| Protein Sequence Length: 447 Download |
| MAPKAKNGLR VAFIHPDLGI GGAERLVVDA ATELVRCGNH VDMYTAYYDP KRCFEETKTG 60 GFAVFTAGSW FPRHVYGRML ALCAYVRCVL VALHIAWRCY KPGPKAAYDV VIADQVAVVV 120 PIVKLLMPST KVLFYCHFPD LLLTKRESFL KKLYRAPLDY LEEATTGAAD LILVNSKYTR 180 SVFAQTFRRL AARAMQPGVL YPAVPIPAES DLRDAEAKWR SELEPELAQF IDGGTTFLSI 240 NRFERKKGIR LALEALCELR ERQGTSRTKS TSTMATVPSA TEGSAAAPPP RARLVVAGGY 300 DPRLPENVEY LKELREAARQ MGLLEVVRFM PSFTDRQRTL LLAACRAVLY TPQHEHFGIV 360 PLEAMAAGRP VVACDSGGPT ESVTHGAVGF LCAPAAAAFA SAMAELMDAE TAVGMGRRAR 420 AHVEGKFSRR AFGEALDGYV RQLRQV* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00534 | Glycos_transf_1 | 2.0e-18 | 294 | 422 | 131 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. | ||
| cd03811 | GT1_WabH_like | 5.0e-21 | 10 | 392 | 388 | + This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core. | ||
| COG0438 | RfaG | 2.0e-21 | 9 | 445 | 440 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| cd03801 | GT1_YqgM_like | 7.0e-26 | 10 | 436 | 431 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
| cd03805 | GT1_ALG2_like | 1.0e-170 | 9 | 436 | 430 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACU21459.1 | 0 | 1 | 445 | 1 | 403 | unknown [Glycine max] |
| RefSeq | NP_178001.2 | 0 | 1 | 440 | 1 | 393 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | XP_001701173.1 | 0 | 2 | 443 | 1 | 433 | glycosyl transferase, group 1 [Chlamydomonas reinhardtii] |
| RefSeq | XP_001778889.1 | 0 | 1 | 443 | 1 | 407 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002525620.1 | 0 | 1 | 443 | 1 | 402 | alpha-1,3-mannosyltransferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2f9f_A | 0.000000000005 | 234 | 406 | 23 | 159 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
| PDB | 2jjm_L | 0.00000003 | 341 | 427 | 281 | 369 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_K | 0.00000003 | 341 | 427 | 281 | 369 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_J | 0.00000003 | 341 | 427 | 281 | 369 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_I | 0.00000003 | 341 | 427 | 281 | 369 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| GO874725 | 380 | 9 | 383 | 0 |
| EL447187 | 360 | 1 | 358 | 0 |
| CK274325 | 352 | 9 | 359 | 0 |
| EL456052 | 355 | 9 | 363 | 0 |
| GO851037 | 326 | 9 | 332 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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