| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_001517m |
| Family | GT20 |
| Protein Properties | Length: 866 Molecular Weight: 97778.1 Isoelectric Point: 5.961 |
| Chromosome | Chromosome/Scaffold: 03352 Start: 7888 End: 13248 |
| Description | trehalose-phosphatase/synthase 9 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 60 | 549 | 0 |
| CRERKIIVANMLPLQAKKDPGTAKWCFSWDEDSLFLQLKDGFSPETEVIYVGSLKADIDATDQEEVSQKLLEDFNCVPTFLPQDLQRKFYLGFCKQQLWP LFHYMLPMCPDHGDRFDRNLWQAYVSANKIFADKVMEIISPDEDYVWIHDYHLMLLPTFLRKGYNRVKLGFFLHSPFPSSEIYRTLPVRDEILRGLLNCD LIGFQTFDYARHFLSCCSRMLGLDYESKRGHIGLDYFGRTVYIKILPVGIHVCRLESVMNLPYTSAKVKEIQEQFSGKKVILGIDDMDIFKGISLKLLAM EQLLQQHPDLQGKVVLVQIVNPARGSGKDVQEAKRETYLIAKRINDVYGSHEYEPVILIDRPVPRYEKTAYYAVAECCIVNAVRDGMNLVPYKYIVCRQG TPYMDKAMGITSDSPRTSMLVVSEFVGCSPSLSGAIRVNPWDIDAVADALNLAITMRESEKQLRHEKHYRYVSTHDVAYWARSFMQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 866 Download |
| MVSRSCMNFL DLASGNLLEI PHTPRSIPRV MTVPGIISDL DGYGPYGSND EDSEIASSIC 60 RERKIIVANM LPLQAKKDPG TAKWCFSWDE DSLFLQLKDG FSPETEVIYV GSLKADIDAT 120 DQEEVSQKLL EDFNCVPTFL PQDLQRKFYL GFCKQQLWPL FHYMLPMCPD HGDRFDRNLW 180 QAYVSANKIF ADKVMEIISP DEDYVWIHDY HLMLLPTFLR KGYNRVKLGF FLHSPFPSSE 240 IYRTLPVRDE ILRGLLNCDL IGFQTFDYAR HFLSCCSRML GLDYESKRGH IGLDYFGRTV 300 YIKILPVGIH VCRLESVMNL PYTSAKVKEI QEQFSGKKVI LGIDDMDIFK GISLKLLAME 360 QLLQQHPDLQ GKVVLVQIVN PARGSGKDVQ EAKRETYLIA KRINDVYGSH EYEPVILIDR 420 PVPRYEKTAY YAVAECCIVN AVRDGMNLVP YKYIVCRQGT PYMDKAMGIT SDSPRTSMLV 480 VSEFVGCSPS LSGAIRVNPW DIDAVADALN LAITMRESEK QLRHEKHYRY VSTHDVAYWA 540 RSFMQDLERA CQDHYNKRCW GIGFGLGFRV VSLSPSFRKL CIEHIVSAYK RTNRRAIFLD 600 YDGTVVPQTS IVKSPSAEVI SVLKTLCNDQ NNTVFIVSGR GKNSLSEWLD PCERLGIAAE 660 HGYFMRYNKT SDWETNPVTD NDLDWKNIVE PIMRSYTEAT DGSSIEVKES ALVWHHQDAD 720 PDFGSCQAKE LLDHLENVLA NEPAVVKRGQ HIVEVKPQGI SKGSVAEKVL LDMVNHGKPP 780 DFVLCIGDDK SDEDMFGSIL STVSDPTLPV APEIFACTVG QKPSKAKYYL DDAVDVVKLL 840 QGLATASCPK PKHTEQVLVS FESAI* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 3.0e-174 | 61 | 847 | 832 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 847 | 851 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 62 | 549 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 63 | 844 | 790 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 65 | 548 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAV65494.1 | 0 | 1 | 863 | 1 | 859 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| GenBank | AAV65495.1 | 0 | 1 | 863 | 1 | 859 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| EMBL | CAN78769.1 | 0 | 1 | 865 | 1 | 857 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002264873.1 | 0 | 1 | 859 | 1 | 851 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521023.1 | 0 | 1 | 865 | 1 | 861 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 142 | 549 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 142 | 549 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 142 | 549 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 142 | 549 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 142 | 549 | 71 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 795 | 73 | 863 | 0 |
| HO779327 | 522 | 95 | 616 | 0 |
| HO779327 | 254 | 613 | 866 | 0 |
| HO797286 | 469 | 380 | 847 | 0 |
| HO777775 | 79 | 1 | 79 | 0.025 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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