| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_001537m |
| Family | GT20 |
| Protein Properties | Length: 862 Molecular Weight: 97323 Isoelectric Point: 6.3365 |
| Chromosome | Chromosome/Scaffold: 02906 Start: 85474 End: 90460 |
| Description | trehalose-phosphatase/synthase 9 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 52 | 546 | 0 |
| NASSICRERIIIVANMLPLHAKKDPETAKWFFSWDEDSLYLQLKDGLSPETEVIYVGSLKADIKASEQEEVSQQLLENFNCVPTFLPQDLQKKFYLGFCK QQLWPLFHYMLPMCPDHGDRFERVVWQAYVSANKMFADKVMEIISPEEDYVWVHDYHLMLLPTFLRKAYNRVKLGFFLHSPFPSSEIYRTLPVRDEILRG LLNCDLIGFHTFDYARHFLSCCSRMLGLDYESKRGHIGLDYFGRTVYIKILPVGIHMGRLESVMNLPSTSVKVKEIQEQLGGRKVILGIDDMDIFKGISL KLLAMEQLLQQHPELRGKVVLVQIVNPARGSGKDVQEAKRETYLTAKRINEVYGSPKYEPVILIDRPVPRYEKTAYYALAECCIVSAVRDGMNLVPYKYI VCRQGTLYMDKAMGTASDSPRKSMIVVSEFIGCSPSLSGAIRVNPWDIDAVADALNLAITMPESEKQLRHEKHYRYVSTHDVAYWARSFMQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 862 Download |
| MVSRSCLNIL DLASGNLLEI PHTPRSIPRV MTVPGIISDL DGYGSNDGDS ENASSICRER 60 IIIVANMLPL HAKKDPETAK WFFSWDEDSL YLQLKDGLSP ETEVIYVGSL KADIKASEQE 120 EVSQQLLENF NCVPTFLPQD LQKKFYLGFC KQQLWPLFHY MLPMCPDHGD RFERVVWQAY 180 VSANKMFADK VMEIISPEED YVWVHDYHLM LLPTFLRKAY NRVKLGFFLH SPFPSSEIYR 240 TLPVRDEILR GLLNCDLIGF HTFDYARHFL SCCSRMLGLD YESKRGHIGL DYFGRTVYIK 300 ILPVGIHMGR LESVMNLPST SVKVKEIQEQ LGGRKVILGI DDMDIFKGIS LKLLAMEQLL 360 QQHPELRGKV VLVQIVNPAR GSGKDVQEAK RETYLTAKRI NEVYGSPKYE PVILIDRPVP 420 RYEKTAYYAL AECCIVSAVR DGMNLVPYKY IVCRQGTLYM DKAMGTASDS PRKSMIVVSE 480 FIGCSPSLSG AIRVNPWDID AVADALNLAI TMPESEKQLR HEKHYRYVST HDVAYWARSF 540 MQDLERACQD HYNKRCWGIG FGLGFRVVSL SPSFRRLGVE HIVSAYKRTN RRAIFLDYDG 600 TVVPHTSIVK SPSPEVMSVL TTLCNDPNNT VFIVSGRARN SLSEWLDPCE RLGIAAEHGY 660 FMRWDKTCEW ETKSVADDLD WKNIVEPIMG LYTETTDGSN IELKESALVW HHQDADPDFG 720 SCQAKELLDH LENVLANEPA VVKRGQHIVE VKPQGISKGF VAEKVLLNMV NRGKPPDFVL 780 CIGDDKSDED MFESILSTVS GPTLTVAPEI FACTVGRKPS KAKYYLDDTV DVVKLLQGLS 840 AASCPKPKCI ENILVSFESA I* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 6.0e-175 | 58 | 843 | 826 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 843 | 848 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 59 | 546 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 60 | 842 | 795 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 60 | 545 | 486 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAV65494.1 | 0 | 1 | 859 | 1 | 859 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| GenBank | AAV65495.1 | 0 | 1 | 859 | 1 | 859 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| EMBL | CAN78769.1 | 0 | 1 | 861 | 1 | 857 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002264873.1 | 0 | 1 | 848 | 1 | 844 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521023.1 | 0 | 1 | 861 | 1 | 861 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 139 | 546 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 139 | 546 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 139 | 546 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 139 | 546 | 70 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 139 | 546 | 71 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 785 | 81 | 859 | 0 |
| HO779327 | 515 | 99 | 613 | 0 |
| HO779327 | 253 | 610 | 862 | 0 |
| HO797286 | 467 | 377 | 843 | 0 |
| HO777775 | 78 | 1 | 77 | 0.0005 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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