| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_001541m |
| Family | GT20 |
| Protein Properties | Length: 862 Molecular Weight: 97417.7 Isoelectric Point: 6.874 |
| Chromosome | Chromosome/Scaffold: 04083 Start: 252872 End: 255764 |
| Description | trehalose phosphate synthase |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 58 | 546 | 0 |
| GKKQIIVANFLPLHAQKDLNSSKWSFSFDEDSILLQMKDGFSINTEVVYVGSLKVDVDTSEQEEVSQKLLEEFNCVPTFLPPDLHKKFYHGFCKHQLWPL FHYMLPMFPDHGERFDKLLWQAYVSANKVFADKVMEVINPEEDYVWVHDYHLMVLPTFLRKRFYRIKLGFFLHSPFPSSEIYRNLPVRDEILKALLNADL IGFHTFDYARHFLSCCSRMLGLDYESKRGHIGLEYFGRTVYIKILPVGVHMGRLESALNHPSSSIKVKEIKKQFEGKRIIVGADDMDIFKGISLKLLAME HLLQQNPELRGKVVMVQIVNPARSSGKDVQEAKKETYSITKRINRIFGFPGYEPVVLIDRHVPFYEKTAYYALAECCIVNAVRDGMNLIPYKYIVCRQGT PKMDEALGINHQLPHSSTIVVSEFIGCSPSLSGAIRVNPWDVEAVADALNLALTMPDLEKQLRHEKHYRYISSHDVAYWARSFMQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 862 Download |
| MMSRSCINLL DLASGDMLNL PRTPRSLPRV MTVPGIFSDT DGDGSNDGDS DAPSSGCGKK 60 QIIVANFLPL HAQKDLNSSK WSFSFDEDSI LLQMKDGFSI NTEVVYVGSL KVDVDTSEQE 120 EVSQKLLEEF NCVPTFLPPD LHKKFYHGFC KHQLWPLFHY MLPMFPDHGE RFDKLLWQAY 180 VSANKVFADK VMEVINPEED YVWVHDYHLM VLPTFLRKRF YRIKLGFFLH SPFPSSEIYR 240 NLPVRDEILK ALLNADLIGF HTFDYARHFL SCCSRMLGLD YESKRGHIGL EYFGRTVYIK 300 ILPVGVHMGR LESALNHPSS SIKVKEIKKQ FEGKRIIVGA DDMDIFKGIS LKLLAMEHLL 360 QQNPELRGKV VMVQIVNPAR SSGKDVQEAK KETYSITKRI NRIFGFPGYE PVVLIDRHVP 420 FYEKTAYYAL AECCIVNAVR DGMNLIPYKY IVCRQGTPKM DEALGINHQL PHSSTIVVSE 480 FIGCSPSLSG AIRVNPWDVE AVADALNLAL TMPDLEKQLR HEKHYRYISS HDVAYWARSF 540 MQDLERACKD HYSKRCWGIG FGLNFRILSL SPSFRKLSNE HIVSAYKKTY RRVIFLDYDG 600 TVVPQTSIVK TPSSEVISVL NNLCSDPKNT VFIVSGRGKD PLSDWFAQCE NLGIAAEHGY 660 LMRWNKTSSW ETSSLVADFD WKRIAVPVIK LYTEATDGSY IETKESALVW HHQYADPDFG 720 SCQAKELLDH LENVLANEPV VVKRGQHIVE VKPQGVTKGL VAERVLSAMI NNGKSPDFVM 780 CIGDDRSDED MFESISRTAS SLSFCSAPEI FACTVGQKPS KARYYLDDTV DVLALLQGLA 840 NASSSKLRVS TEVQVSFDNL V* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 5.0e-176 | 57 | 845 | 830 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 847 | 852 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 59 | 546 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 59 | 842 | 791 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 62 | 545 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN78769.1 | 0 | 1 | 861 | 1 | 857 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002283215.1 | 0 | 1 | 861 | 1 | 862 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318643.1 | 0 | 1 | 861 | 1 | 857 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322159.1 | 0 | 1 | 861 | 1 | 861 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511428.1 | 0 | 1 | 859 | 1 | 859 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 144 | 546 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 144 | 546 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 144 | 546 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 144 | 546 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1uqu_B | 0 | 144 | 546 | 75 | 453 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 789 | 70 | 852 | 0 |
| HO779327 | 515 | 99 | 613 | 0 |
| HO779327 | 253 | 610 | 862 | 0 |
| HO797286 | 478 | 376 | 852 | 0 |
| HO777775 | 75 | 1 | 74 | 2 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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