| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_001591m |
| Family | GT20 |
| Protein Properties | Length: 854 Molecular Weight: 96042.6 Isoelectric Point: 6.2779 |
| Chromosome | Chromosome/Scaffold: 08127 Start: 154049 End: 159234 |
| Description | trehalose-phosphatase/synthase 7 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 59 | 546 | 0 |
| VQDRIIIVANQLPVKAKRRPDNKGWGFSWDEDSLLLQLKDGLPEDMEVIYVGSLRVEVDLSEQDDVSQLLLDRFKCVPAFLPPDILSKFYHGFCKQHLWP LFHYMLPFSASHGGRFDRSLWEAYVAANKIFSQRVVEVLNPEDDYVWIHDYHLMVLPTFLRRRFNRLRMGFFLHSPFPSSEIYRTLPVREEILKALLNSD LIGFHTFDYARHFLSCCSRMLGLEYQSKRGYIGLEYYGRTVGIKIMPVGIHMGQIESVLRLADKEWRVGELKQQFEGKTVLLGVDDMDIFKGVNLKLLAM EQMLKQHPKWQGRAVLVQIANPARGKGKDLEEIQAEIQASCKRINETFGQPGYEPVVFIDRPVSLSERAAYYTVAECVVVAAVRDGMNLTPYEYIVCRQG VSGSESSSESSGPKKSMLVVSEFIGCSPSLSGAIRVNPWNIEATAEAMNEAISMSESEKQLRHEKHYRYVSTHDVAYWSKSFFQDMER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 854 Download |
| MMSRSYTNLL DLASGNFPVM GQPREKKRLP RVMTVPGVIS ELDDDQANSV ASDVPSSLVQ 60 DRIIIVANQL PVKAKRRPDN KGWGFSWDED SLLLQLKDGL PEDMEVIYVG SLRVEVDLSE 120 QDDVSQLLLD RFKCVPAFLP PDILSKFYHG FCKQHLWPLF HYMLPFSASH GGRFDRSLWE 180 AYVAANKIFS QRVVEVLNPE DDYVWIHDYH LMVLPTFLRR RFNRLRMGFF LHSPFPSSEI 240 YRTLPVREEI LKALLNSDLI GFHTFDYARH FLSCCSRMLG LEYQSKRGYI GLEYYGRTVG 300 IKIMPVGIHM GQIESVLRLA DKEWRVGELK QQFEGKTVLL GVDDMDIFKG VNLKLLAMEQ 360 MLKQHPKWQG RAVLVQIANP ARGKGKDLEE IQAEIQASCK RINETFGQPG YEPVVFIDRP 420 VSLSERAAYY TVAECVVVAA VRDGMNLTPY EYIVCRQGVS GSESSSESSG PKKSMLVVSE 480 FIGCSPSLSG AIRVNPWNIE ATAEAMNEAI SMSESEKQLR HEKHYRYVST HDVAYWSKSF 540 FQDMERTCKD HFRRRCWGIG FSFGFRVVAL DPNFRKLSTD AIVSAYLRSK NRAILLDYDG 600 TVMPQTSINK TPSQEVISII NALCGDVKNT VFIVSGRGRE SLGKWFSPCK KLGIAAEHGY 660 FIRWSVDEQW ETCGQNSDFG WIHIAEPVMK LYTESTDGSS IETKESALVW HHRDADPGFG 720 ASQAKEMLDH LESVLANEPV AVKSGQFIVE VKPQGISKGF VAERIFTSMV ERGKQADFVL 780 CIGDDRSDED MFEIIGNATA NGVLSSSTSV FACTVGQKPS KAKYYLDDTT EVINMLEALA 840 EASDSSPSPG NSP* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 4.0e-171 | 62 | 842 | 817 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 840 | 847 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 62 | 546 | 489 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| cd03788 | GT1_TPS | 0 | 62 | 545 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| PRK14501 | PRK14501 | 0 | 62 | 842 | 790 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACD56638.1 | 0 | 1 | 844 | 1 | 844 | trehalose synthase-like protein [Gossypioides kirkii] |
| RefSeq | XP_002268174.1 | 0 | 1 | 849 | 1 | 846 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002305726.1 | 0 | 1 | 853 | 1 | 849 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002317392.1 | 0 | 1 | 853 | 1 | 853 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522255.1 | 0 | 1 | 842 | 1 | 842 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 144 | 546 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 144 | 546 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 144 | 546 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 144 | 546 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 144 | 546 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 764 | 83 | 840 | 0 |
| HO779327 | 513 | 103 | 613 | 0 |
| HO779327 | 232 | 609 | 840 | 0 |
| HO795511 | 466 | 376 | 841 | 0 |
| HO777775 | 80 | 1 | 79 | 0.0000001 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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