| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_002727m |
| Family | GT2 |
| Protein Properties | Length: 702 Molecular Weight: 80504.6 Isoelectric Point: 8.0193 |
| Chromosome | Chromosome/Scaffold: 09127 Start: 56055 End: 59062 |
| Description | Cellulose-synthase-like C12 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT2 | 248 | 424 | 2e-30 |
| VQIPMCNEKEVYQQSIAAACNLDWPKSKILVQVLDDSDDPTTQLLIKEEVNKWQQEGAHIVYRHRVVRQGYKAGNLKSAMNCSYVKDYEFVAIFDADFQP APDFLKRTVPHFKDNEELALVQARWSFVNREENLLTRLQNINLAFHFEVEQQVNGVFINFFGFNGTAGVWRIKALED | |||
| Full Sequence |
|---|
| Protein Sequence Length: 702 Download |
| MALSFNWWAK EGHRGTPVVV KMENPNWSMV ELEGPSDEDF LIGDSPSRPI DKSRNKNARQ 60 LTWVLFLKAH KAAGYLTSIA SSTVSIGSVI KRRLRSGRTD TDPEVDGDVG LENENPTVKS 120 RFYFCIKVFL WLSVLLLGFE MAAYFKGWHF GSPHLQLQYL LATPFGFKDI FDSLYSRWVL 180 IRVEYLAPPL QFLANVCIVL FLVQSLDRLV LCLGCFWIRF KKIKPIPKQD AIADLESGED 240 GFFPMVLVQI PMCNEKEVYQ QSIAAACNLD WPKSKILVQV LDDSDDPTTQ LLIKEEVNKW 300 QQEGAHIVYR HRVVRQGYKA GNLKSAMNCS YVKDYEFVAI FDADFQPAPD FLKRTVPHFK 360 DNEELALVQA RWSFVNREEN LLTRLQNINL AFHFEVEQQV NGVFINFFGF NGTAGVWRIK 420 ALEDAGGWLE RTTVEDMDIA VRAHLHGWKF IFLNDVECQC ELPESYEAYR KQQHRWHSGP 480 MQLFRLCLPD IIRSKISIWK KFNMIFLFFL LRKLILPFYS FTLFCIILPM TMFIPEAELP 540 AWIVCYVPAT MSFLNILPAP KSFPFIVPYL LFENTMSVTK FNAMISGLFQ LGSAYEWVVT 600 KKSGRSSEGD LVSLAAKEPN NQRVASVPNL VEMKADIQQE QKARKKKHNR IYTKELALAF 660 LLLAASARSL LSAQGIHFYF LLFQGISFLL VGFDLIGEQV Q* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06423 | CESA_like | 8.0e-34 | 248 | 436 | 189 | + CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan. | ||
| cd06435 | CESA_NdvC_like | 3.0e-34 | 248 | 485 | 240 | + NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response. | ||
| COG1215 | COG1215 | 1.0e-38 | 186 | 589 | 407 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
| cd06421 | CESA_CelA_like | 2.0e-50 | 244 | 484 | 247 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. | ||
| cd06437 | CESA_CaSu_A2 | 6.0e-110 | 244 | 480 | 237 | + Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_192536.1 | 0 | 1 | 701 | 1 | 699 | ATCSLC12 (CELLULOSE-SYNTHASE LIKE C12); cellulose synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002285486.1 | 0 | 1 | 701 | 1 | 699 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002302382.1 | 0 | 1 | 701 | 1 | 701 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307301.1 | 0 | 1 | 701 | 1 | 701 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510040.1 | 0 | 1 | 701 | 1 | 696 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4hg6_A | 4e-27 | 184 | 608 | 87 | 514 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |
