| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_002754m |
| Family | GT47 |
| Protein Properties | Length: 699 Molecular Weight: 80066.6 Isoelectric Point: 9.1296 |
| Chromosome | Chromosome/Scaffold: 00847 Start: 647065 End: 652058 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 367 | 649 | 0 |
| RMLKVYIYKDGKKPIFHLPILKGLYASEGWFMKLMQGNRHFVVKDPRKAHLFYMPFSSRMLEYTIYVRNSHNRTNLRQYLKEYTEKIAAKYPYWNRTGGA DHFLVACHDWAPYETRHHMEHCIKALCNADVTSGFKIGRDVSLPETYVRSARNPLRDLGGKPPSQRHILAFYAGNMHGYLRPILLKHWKDKDPSMKIFGP MPPGVASKMNYIQHMKNSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVFNWGAFSVILEEKDIPNLKEILLSV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 699 Download |
| MELRFHFHKL CQIETRRWLL VVGAVAITHL LFQSLLLPYG NALRSLLPNS NDIINDKTSF 60 PIIQSSTKSL IVRNPLTVDT SSFTKGHILD RVVVKDAIAS GGSGDISHDS ESQRKSGDTD 120 SDFTSEDEDL DNPFELAVDN DGDNDDFVEE GLNNPIGLLV DRNVNEFPSG NGMHSNGTSS 180 LESIESKGSD SIMEFTSESK HEFPLDQNGK LNDEISIENN LPLKDLQRIK VAVKSYPLEP 240 KVVTSSKNIS YSRSNGNSSI GSAILKDDFA TSKNDSAKMV KPARKKMRCE MPPNSVTSID 300 DMNLILARHR RSSRSMRPRW SSHHDQEILA ARSQIENAPI PVNDHDLYAP LFRNVSKFKR 360 SYELMERMLK VYIYKDGKKP IFHLPILKGL YASEGWFMKL MQGNRHFVVK DPRKAHLFYM 420 PFSSRMLEYT IYVRNSHNRT NLRQYLKEYT EKIAAKYPYW NRTGGADHFL VACHDWAPYE 480 TRHHMEHCIK ALCNADVTSG FKIGRDVSLP ETYVRSARNP LRDLGGKPPS QRHILAFYAG 540 NMHGYLRPIL LKHWKDKDPS MKIFGPMPPG VASKMNYIQH MKNSKYCICP KGYEVNSPRV 600 VEAIFYECVP VIISDNFVPP FFEVFNWGAF SVILEEKDIP NLKEILLSVP EKKYLELQLG 660 VKKVQRHFLW HPNPVKYDLF YMTLHSIWYN RVYQIKPR* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-64 | 369 | 649 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76867.1 | 0 | 1 | 694 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76867.1 | 0 | 1 | 696 | 1 | 711 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_197468.1 | 0 | 165 | 698 | 87 | 600 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002283936.1 | 0 | 291 | 698 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514248.1 | 0 | 1 | 698 | 1 | 676 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EG631332 | 278 | 422 | 699 | 0 |
| ES808098 | 337 | 332 | 668 | 0 |
| JG174792 | 264 | 436 | 699 | 0 |
| DV712689 | 315 | 275 | 589 | 0 |
| EV026079 | 246 | 373 | 618 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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