| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_003164m |
| Family | GT2 |
| Protein Properties | Length: 663 Molecular Weight: 76583.7 Isoelectric Point: 8.9048 |
| Chromosome | Chromosome/Scaffold: 01195 Start: 36625 End: 39088 |
| Description | Cellulose-synthase-like C4 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT2 | 204 | 380 | 6.3e-29 |
| VQIPMCNEREVYAQSISAACQLDWPRDRLLIQVLDDSDDGNVQLLIKDEVSSWRQKGINIIYRHRLIRTGYKAGNLNSAMSCDYVQDYEFVAIFDADFQP NPDFLKQTVPHFKGNPELGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGAFLNFFGFNGTAGVWRIKALED | |||
| Full Sequence |
|---|
| Protein Sequence Length: 663 Download |
| MAPNSVVVTL EKPKDFSIVE INASDPSLFP EKQKAASPKQ FTWVLLLKIY KALTCVSWFA 60 MVFKSTFLSI KKRIAFSEMS EEEPRSRGRL YRFIKAFLAM SIVALVIEIV AHFKKWNLNL 120 IHPWEIQGLV QWSYMAWFSF RVHYIAPLVI KLSQFCTVLF LIQSLDRLVL CLGCFWIKYK 180 KLKPEINGEA YDIEDPSTFP MVLVQIPMCN EREVYAQSIS AACQLDWPRD RLLIQVLDDS 240 DDGNVQLLIK DEVSSWRQKG INIIYRHRLI RTGYKAGNLN SAMSCDYVQD YEFVAIFDAD 300 FQPNPDFLKQ TVPHFKGNPE LGLVQARWSF VNKDENLLTR LQNINLCFHF EVEQQVNGAF 360 LNFFGFNGTA GVWRIKALED SGGWLERTTV EDMDIAVRAH LNGWKFIFLN DVKVLCELPE 420 SYEAYKKQQH RWHSGPMQLF RLCLPAIITS KISKWKKANL IFLFFLLRKL ILPFYSFTLF 480 CIILPLTMFI PEAELPLWVI CYIPIFMSFL NILPAPKSFP FLVPYLLFEN TMSVTKFNAM 540 VSGLFQLGSA YEWVVTKKTG RSSESDLLAF AERESKSSKE EKIHRRHSES GLELLSKLQE 600 QEAPRVKKRN RIYRKELALA FLLLTAAARS LLSAHGVHFY YLLFQGLSFL VVGLDLIGEQ 660 IS* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06423 | CESA_like | 9.0e-30 | 204 | 392 | 189 | + CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan. | ||
| TIGR03030 | CelA | 2.0e-30 | 194 | 442 | 268 | + cellulose synthase catalytic subunit (UDP-forming). Cellulose synthase catalyzes the beta-1,4 polymerization of glucose residues in the formation of cellulose. In bacteria, the substrate is UDP-glucose. The synthase consists of two subunits (or domains in the frequent cases where it is encoded as a single polypeptide), the catalytic domain modelled here and the regulatory domain (pfam03170). The regulatory domain binds the allosteric activator cyclic di-GMP. The protein is membrane-associated and probably assembles into multimers such that the individual cellulose strands can self-assemble into multi-strand fibrils. | ||
| COG1215 | COG1215 | 1.0e-34 | 144 | 519 | 381 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
| cd06421 | CESA_CelA_like | 5.0e-51 | 200 | 440 | 247 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. | ||
| cd06437 | CESA_CaSu_A2 | 1.0e-106 | 200 | 436 | 237 | + Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN82135.1 | 0 | 1 | 662 | 1 | 695 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI34964.1 | 0 | 1 | 661 | 1 | 628 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_566835.1 | 0 | 1 | 662 | 1 | 673 | ATCSLC04 (CELLULOSE-SYNTHASE LIKE C4); cellulose synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002280124.1 | 0 | 1 | 662 | 1 | 664 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002517383.1 | 0 | 1 | 662 | 1 | 662 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4hg6_A | 8e-24 | 196 | 481 | 136 | 442 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |
