| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_003734m |
| Family | GT47 |
| Protein Properties | Length: 620 Molecular Weight: 70384.2 Isoelectric Point: 7.25 |
| Chromosome | Chromosome/Scaffold: 05806 Start: 150539 End: 152947 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 289 | 570 | 0 |
| RMLKVYIYKDGPKPIFHQPILEGIYASEGWFMKLMEANENFVTKDPREAHLFYIPFSSRLLQLTLYVRKSHNRTNLIEYMKNYVDMVAANHTFWNRTGGA DHFVAACHDWAPAETRGLMLNCIRALCNADIDVGFSIGKDVSLPETYVKSSQNPIKNLEGNPPSQRPFLAFFAGNLHGYVRPILLEYWENKDPNMKIFGP LPHVKGNAIYIQYMKSSKYCICPRGHEVNSPRIVESIFYECVPVIISDNYIPPLFEVLDWESFAVFVPEKDIPDLKNILLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 620 Download |
| MDQGFRFLCQ AEARRLLFLM GATIALLIAI QYFEFPSIRV LSFFSIDNNI SFLPRESSSS 60 NFEMSDNMIP SNGLNSTIAS APHERTNSSE ASFSKKQAAE GNKSKEMEGS AKSNYALESN 120 GGSVNTSGFV SNATTSEDHV AQNKTSILEK GENSVNGSEV EKAMAPEISF TNVTEDVASV 180 SERSRSSDSA AIVNKEENAG PLPSNLSKKK FWKAPSRVVS ISQMNELLQQ SRALSNSVRP 240 LWPLEVDQRM VFARSQIENA PGIENDTVLY APIYRNASMF KRSYELMERM LKVYIYKDGP 300 KPIFHQPILE GIYASEGWFM KLMEANENFV TKDPREAHLF YIPFSSRLLQ LTLYVRKSHN 360 RTNLIEYMKN YVDMVAANHT FWNRTGGADH FVAACHDWAP AETRGLMLNC IRALCNADID 420 VGFSIGKDVS LPETYVKSSQ NPIKNLEGNP PSQRPFLAFF AGNLHGYVRP ILLEYWENKD 480 PNMKIFGPLP HVKGNAIYIQ YMKSSKYCIC PRGHEVNSPR IVESIFYECV PVIISDNYIP 540 PLFEVLDWES FAVFVPEKDI PDLKNILLSI PEKRYVEMHK RVTKVQQHFL WHSEPVKYDL 600 FHMILHSVWY NRVFQMRPA* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-69 | 291 | 570 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002281263.1 | 0 | 1 | 617 | 1 | 667 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002283936.1 | 0 | 215 | 618 | 3 | 409 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309546.1 | 0 | 198 | 619 | 3 | 417 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002309547.1 | 0 | 156 | 618 | 17 | 470 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002516500.1 | 0 | 177 | 619 | 1 | 456 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
