| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_004218m |
| Family | GT1 |
| Protein Properties | Length: 589 Molecular Weight: 64772.2 Isoelectric Point: 6.7375 |
| Chromosome | Chromosome/Scaffold: 02264 Start: 397589 End: 404766 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT1 | 149 | 555 | 0 |
| IVGTRGDVQPFIAIGKRLQEDGHRVRLATHANFKDFVLTAGLEFFPLGGDPKVLAGYMVKNKGFLPSSPSEISIQRHQLRDIIFSLLPACQNPDPDTKIP FKANAIIANPPAYGHTHVAEALKVPIHIFFTMPWTPTSEFPHPLSRVKQPVAYKLSYQIVDSMIWLGIRNIINEFRKKKLKLRPVTYLSGYYSSSPDLPY GYIWSPHLVPKPKDWGPKIDVVGFCFLDLASNYEPPNSLVEWLEGGDPPIYVGFGSLPLQEPEKMTQIIVTALEETGQRGIINKGWGGLGNLAEPKEFVY LLDNCPHDWLFSRCKAVVHHGGAGTTAAGLKVGCPTTIVPFFGDQPFWGEQVHARGLGPAPIPVDEFSLEKLVDAIHFMLDPKVKEHAMELAKAMEEENG VQGAVNA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 589 Download |
| MAESPDNPHR RSCSGDSVVC ENGIASNSSG VIDSSLVKHS VSGETSATGK SDSGSSHQEK 60 SGRHGESYHL SILAAKLFDD RIPFKKKIKL LPQFANIKDD GTVQLEVPGD IKPPSLDLVK 120 VVQDESTDEE PFDTAEPQDI PPLQIVMLIV GTRGDVQPFI AIGKRLQEDG HRVRLATHAN 180 FKDFVLTAGL EFFPLGGDPK VLAGYMVKNK GFLPSSPSEI SIQRHQLRDI IFSLLPACQN 240 PDPDTKIPFK ANAIIANPPA YGHTHVAEAL KVPIHIFFTM PWTPTSEFPH PLSRVKQPVA 300 YKLSYQIVDS MIWLGIRNII NEFRKKKLKL RPVTYLSGYY SSSPDLPYGY IWSPHLVPKP 360 KDWGPKIDVV GFCFLDLASN YEPPNSLVEW LEGGDPPIYV GFGSLPLQEP EKMTQIIVTA 420 LEETGQRGII NKGWGGLGNL AEPKEFVYLL DNCPHDWLFS RCKAVVHHGG AGTTAAGLKV 480 GCPTTIVPFF GDQPFWGEQV HARGLGPAPI PVDEFSLEKL VDAIHFMLDP KVKEHAMELA 540 KAMEEENGVQ GAVNAFYKHF PRQKLEPEPS PKPAHPKCPS IKSCFACH* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 2.0e-30 | 145 | 564 | 431 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 1.0e-32 | 145 | 289 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 2.0e-120 | 145 | 559 | 419 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC22617.1 | 0 | 10 | 587 | 19 | 601 | UDP-glucose:sterol 3-O-glucosyltransferase [Panax ginseng] |
| EMBL | CBI37267.1 | 0 | 56 | 587 | 86 | 614 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265023.1 | 0 | 56 | 587 | 133 | 661 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002512608.1 | 0 | 1 | 588 | 1 | 596 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| RefSeq | XP_002521125.1 | 0 | 17 | 587 | 50 | 625 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 2e-30 | 143 | 564 | 1 | 385 | B Chain B, Crystal Structure Of The Complex Between Pectin Methylesterase And Its Inhibitor Protein |
| PDB | 3h4i_A | 2e-30 | 143 | 564 | 1 | 385 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 4e-22 | 143 | 540 | 1 | 380 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 4e-22 | 143 | 540 | 1 | 380 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1iir_A | 1e-19 | 387 | 564 | 230 | 402 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| GT046352 | 335 | 152 | 486 | 0 |
| GO883166 | 332 | 113 | 438 | 0 |
| HO626576 | 427 | 141 | 561 | 0 |
| CX664063 | 295 | 242 | 536 | 0 |
| GT046352 | 29 | 482 | 510 | 0.004 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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