| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_004684m |
| Family | GT68 |
| Protein Properties | Length: 563 Molecular Weight: 64106.9 Isoelectric Point: 7.5842 |
| Chromosome | Chromosome/Scaffold: 10504 Start: 163941 End: 167158 |
| Description | O-fucosyltransferase family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 244 | 537 | 0 |
| NRVLVMPSSKFDFQYSRVLDIEHINHCLGRKVVVTFEEFAQMRKNHVHIDRFICYFSSPVPCYVDEEHVKRLKGLGISMGKLESPWKEDVKKPSKKTVQD VQAKFTANNDVIAIGDVFFADVEKEWVLQPGGPLAHKCKTLIEPSRLIILTAQRFIQTFLGKNFIALHFRRHGFLKFCNVKKPSCFYPIPQAADCIARVV ERANAPVMYLSTDAAESETDLLQSLILVNGKAVPLVKRPSHTSVEKWDALLSRHGIEGDSQVEAMLDKTICAMSSVFIGASGSTFTEDILRLRK | |||
| Full Sequence |
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| Protein Sequence Length: 563 Download |
| MDRDSSDEED DRHTLIEQND RKPNHHHNHS SPQRRSTSTF HIEETESFGG SIRRRFFRNF 60 NKRNMFSANL SALRLDSVSD RMREAELQAL YLLGQQQLSL LSLLNQSFPF HNNNSNTLSN 120 SNSNTSVNSN ASFEFNNLEE QGLRFKIEDL RSALLKQISL NKQIQQVLLS PHESANVNVS 180 APDFVGSGFG YDRCRKVESR FSDRKTIDWK PRSDKFLFAI CLSGQMSNHL ICLEKHMFFA 240 ALLNRVLVMP SSKFDFQYSR VLDIEHINHC LGRKVVVTFE EFAQMRKNHV HIDRFICYFS 300 SPVPCYVDEE HVKRLKGLGI SMGKLESPWK EDVKKPSKKT VQDVQAKFTA NNDVIAIGDV 360 FFADVEKEWV LQPGGPLAHK CKTLIEPSRL IILTAQRFIQ TFLGKNFIAL HFRRHGFLKF 420 CNVKKPSCFY PIPQAADCIA RVVERANAPV MYLSTDAAES ETDLLQSLIL VNGKAVPLVK 480 RPSHTSVEKW DALLSRHGIE GDSQVEAMLD KTICAMSSVF IGASGSTFTE DILRLRKDWE 540 SASLCDEYLC QGELPNFIAE DE* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11548 | NodZ_like | 0.001 | 382 | 537 | 160 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 0.0001 | 216 | 250 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 8.0e-5 | 239 | 529 | 328 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11298 | O-FucT-2 | 3.0e-7 | 403 | 529 | 129 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 3.0e-15 | 377 | 536 | 173 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM66093.1 | 0 | 1 | 562 | 1 | 566 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_199853.1 | 0 | 1 | 562 | 1 | 566 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 1 | 562 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002303337.1 | 0 | 1 | 562 | 1 | 527 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002533327.1 | 0 | 1 | 562 | 1 | 565 | conserved hypothetical protein [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| GO881872 | 353 | 211 | 560 | 0 |
| ES850268 | 327 | 204 | 528 | 0 |
| CO085239 | 287 | 260 | 545 | 0 |
| EX128555 | 296 | 206 | 500 | 0 |
| ES850268 | 47 | 509 | 553 | 2.2 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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