| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_005358m |
| Family | GT57 |
| Protein Properties | Length: 531 Molecular Weight: 60940.2 Isoelectric Point: 8.8552 |
| Chromosome | Chromosome/Scaffold: 08265 Start: 3672269 End: 3676067 |
| Description | ALG6, ALG8 glycosyltransferase family |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT57 | 26 | 522 | 0 |
| ACIKLLLVPSYHSTDFEVHRHWLALTHSLPLTQWYFDETSPWTLDYPPFFAYYEYILSFFAHLIDPQIVDIHRGLNYKSNTVVYFQRISVIVSDLCLLYG VYRLTKNLESRKRTLMWVLVVWSPGLIMVDSMHFQYNGFLLGLLMLSISYLQEGRDLMGGFFFAVLLCFKHLFAVAAPVYFVYLLRHYCWKGFLRGFGRL TSMGVVVMVVFAAAYGPFLYHGQIQQVISRMFPFGRGLCHAYWAPNFWVFYITLDKGLSIFLKKLGLDIQAPAASFTGGLVGDSPSFAVLPKITPIATFI MVLLALFPCLFKAWKNPQPQLVARWIAYAYTCGFLFGWHVHEKASLHFVIPLALVAVHSLEDARHYFLLAIVSCYSLFPLLYEVQEYPIKVLLLLLHSIL MWHSFSAQTTKDPAAKMAVSAKREKRSSSLGALDATVEKERILIGWIGKCYLFGLLGIEIWGQFLHPYLLGDKLPFVPLLLVSLYCAFGMIYSWIWQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 531 Download |
| MEGQKFQMHE TSTNSQLLFW FFGIAACIKL LLVPSYHSTD FEVHRHWLAL THSLPLTQWY 60 FDETSPWTLD YPPFFAYYEY ILSFFAHLID PQIVDIHRGL NYKSNTVVYF QRISVIVSDL 120 CLLYGVYRLT KNLESRKRTL MWVLVVWSPG LIMVDSMHFQ YNGFLLGLLM LSISYLQEGR 180 DLMGGFFFAV LLCFKHLFAV AAPVYFVYLL RHYCWKGFLR GFGRLTSMGV VVMVVFAAAY 240 GPFLYHGQIQ QVISRMFPFG RGLCHAYWAP NFWVFYITLD KGLSIFLKKL GLDIQAPAAS 300 FTGGLVGDSP SFAVLPKITP IATFIMVLLA LFPCLFKAWK NPQPQLVARW IAYAYTCGFL 360 FGWHVHEKAS LHFVIPLALV AVHSLEDARH YFLLAIVSCY SLFPLLYEVQ EYPIKVLLLL 420 LHSILMWHSF SAQTTKDPAA KMAVSAKREK RSSSLGALDA TVEKERILIG WIGKCYLFGL 480 LGIEIWGQFL HPYLLGDKLP FVPLLLVSLY CAFGMIYSWI WQLRCIMIST * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03155 | Alg6_Alg8 | 4.0e-102 | 23 | 521 | 514 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI16712.1 | 0 | 1 | 530 | 1 | 472 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_181994.5 | 0 | 9 | 527 | 3 | 505 | transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
| Swiss-Prot | O80505 | 0 | 9 | 408 | 3 | 402 | ALG8_ARATH RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; AltName: Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 8 homolog |
| RefSeq | XP_002269114.1 | 0 | 1 | 530 | 1 | 532 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521523.1 | 0 | 1 | 530 | 1 | 493 | dolichyl glycosyltransferase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5471 | EC-2.4.1.265 | Dol-P-Glc:Glc1Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |
