| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_005963m |
| Family | GT47 |
| Protein Properties | Length: 507 Molecular Weight: 57884.8 Isoelectric Point: 9.5818 |
| Chromosome | Chromosome/Scaffold: 03614 Start: 923995 End: 927940 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 118 | 428 | 0 |
| IRVYVYEMPRKFTYDLLWLFRNTYRETDNLTSNGSPVHRLIEQHSIDYWLWADLIAPESERLLKSVVRVHRQEEADLFYIPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSGGRDHILPVHHPWSFKSVRRYMKNAIWLLPDMDSTGNWYKPGQVFLEKDLILPYVPNVDLCDARCLSKSESKRTTLLFFRGRLK RNAGGKIRAKLVSELSGADGVIIEEGTAGDGGKSAAQIGMRKSIFCLNPAGDTPSSARLFDAIVSGCIPVIISDELELPFEGILDYRKIALFVSSSDAMQ PGWLLKFLKGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 507 Download |
| MRSKLHITPS SRSRSPILLL TLSFLAISLL FFLFSLSSSQ TRIQSPYLNP SLAFKPETSF 60 LASLEHFLAE KAPRSSSTRD DTVIQVTDEE VTELDKEMYR KESERVSGNP YYPLEFPIRV 120 YVYEMPRKFT YDLLWLFRNT YRETDNLTSN GSPVHRLIEQ HSIDYWLWAD LIAPESERLL 180 KSVVRVHRQE EADLFYIPFF TTISFFLLEK QQCKALYREA LKWVTDQPAW KRSGGRDHIL 240 PVHHPWSFKS VRRYMKNAIW LLPDMDSTGN WYKPGQVFLE KDLILPYVPN VDLCDARCLS 300 KSESKRTTLL FFRGRLKRNA GGKIRAKLVS ELSGADGVII EEGTAGDGGK SAAQIGMRKS 360 IFCLNPAGDT PSSARLFDAI VSGCIPVIIS DELELPFEGI LDYRKIALFV SSSDAMQPGW 420 LLKFLKGIGA AQVREMRQKL GQYSRHFLYS SPAQPLGPED LVWRMMAGKL VNIKLHTRRS 480 QRVVKESRSI CTCDCKRANF TGPNIV* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-69 | 117 | 428 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 125 | 503 | 1 | 379 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 6 | 497 | 8 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 56 | 503 | 62 | 513 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 46 | 501 | 47 | 501 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 1 | 506 | 1 | 507 | catalytic, putative [Ricinus communis] |
