| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_006429m |
| Family | GT47 |
| Protein Properties | Length: 489 Molecular Weight: 55840.4 Isoelectric Point: 9.8471 |
| Chromosome | Chromosome/Scaffold: 08359 Start: 2025927 End: 2028263 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 111 | 427 | 0 |
| LLRVYMYDLPPEFHFGLLDWKRKANQTWPNVLDHIPPYPGGLNLQHSMEYWLTLDLLASSTPDVRRPCSAVRVQNSSLADIIFVPFFSSLSYNRHSKVYE KEKVSVNQRLQDRLVQVLMGQDEWKRFGGRDHLIVAHHPNSMLDARKMLGSAMFILADFGRYPVEIANPGKDIIAPYKHVVRTISSGESAQFDGRPILVF FQGAIYRKDRGVIRQELYYLLRDEKDVHFTFGTVRGNGINKASQGMASSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDEIELPFEDVLDYSEFSVFVR ASDAVKKGYLLNLLRNI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 489 Download |
| MSEKSRLSSR FLFFLIPVSM FFFIISSVSL LQLGNISLLP GSIFKLILVN STSFYLKSND 60 KSEPVKIPIF SSMPSQIDTK SSMRSGVKCP NSEIAAIGKN KKKNCDPNQA LLRVYMYDLP 120 PEFHFGLLDW KRKANQTWPN VLDHIPPYPG GLNLQHSMEY WLTLDLLASS TPDVRRPCSA 180 VRVQNSSLAD IIFVPFFSSL SYNRHSKVYE KEKVSVNQRL QDRLVQVLMG QDEWKRFGGR 240 DHLIVAHHPN SMLDARKMLG SAMFILADFG RYPVEIANPG KDIIAPYKHV VRTISSGESA 300 QFDGRPILVF FQGAIYRKDR GVIRQELYYL LRDEKDVHFT FGTVRGNGIN KASQGMASSK 360 FCLNIAGDTP SSNRLFDAIV SHCVPVIISD EIELPFEDVL DYSEFSVFVR ASDAVKKGYL 420 LNLLRNIERD KWTMMWERLK NIAPQFEYQY PSQPGDAVDM IWKAISRKRS SVQFTLNRKN 480 RYQRTEIQ* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-58 | 112 | 427 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD55303.1 | 0 | 1 | 487 | 1 | 451 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
| RefSeq | XP_002284930.1 | 0 | 1 | 487 | 1 | 450 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002284932.1 | 0 | 93 | 487 | 15 | 411 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
| RefSeq | XP_002320639.1 | 0 | 112 | 484 | 3 | 374 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002514760.1 | 0 | 1 | 488 | 1 | 490 | catalytic, putative [Ricinus communis] |
