y
Basic Information | |
---|---|
Species | Manihot esculenta |
Cazyme ID | cassava4.1_006525m |
Family | GT47 |
Protein Properties | Length: 485 Molecular Weight: 54899.1 Isoelectric Point: 8.8653 |
Chromosome | Chromosome/Scaffold: 06814 Start: 543440 End: 546706 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 63 | 409 | 0 |
NPIKVYLADLPRSFNYGLLDQYWSSSVPDSRISYDPDHSQIYGYKSSKFPPYPENPLIKQYSAEYWLMGDLMTPEHLRIQSFAKRVVDVDQADVVFVPFF ATLSAEMELGRGKGTFRRKEGNEDYKRQKEVIELVKNSDAWKRSGGRDHVFVLTDPVAMWHVRAEIAPSILLVVDFGGWYRLDSKSSNGSSSNMIQHTQV SLLKDIIVPYTHLLPRLHLAENERRKTLLYFKGAKHRHRGGVVRENMWDLLVNEPGVIMEEGFPNATGREQSIRGMRTSEFCLHPAGDTPTSCRLFDAIQ SLCIPVIVSDNIELPFEGMVDYSEFSVFVAVNDALKPSWLVNHLKSI |
Full Sequence |
---|
Protein Sequence Length: 485 Download |
MPPKNTVDSI SAATKTTTLP CSIPSLFLTF TVFSFITLSF FLLFSNPNPS IPNLQNTLQA 60 PQNPIKVYLA DLPRSFNYGL LDQYWSSSVP DSRISYDPDH SQIYGYKSSK FPPYPENPLI 120 KQYSAEYWLM GDLMTPEHLR IQSFAKRVVD VDQADVVFVP FFATLSAEME LGRGKGTFRR 180 KEGNEDYKRQ KEVIELVKNS DAWKRSGGRD HVFVLTDPVA MWHVRAEIAP SILLVVDFGG 240 WYRLDSKSSN GSSSNMIQHT QVSLLKDIIV PYTHLLPRLH LAENERRKTL LYFKGAKHRH 300 RGGVVRENMW DLLVNEPGVI MEEGFPNATG REQSIRGMRT SEFCLHPAGD TPTSCRLFDA 360 IQSLCIPVIV SDNIELPFEG MVDYSEFSVF VAVNDALKPS WLVNHLKSIS EKQRNEYRQK 420 MAKVQPLFIY DNGHPGGIGP IPPDGAVNHI WKKVQQKLPM IKETIVREKR KPAGVSIPLR 480 CHCT* 540 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-56 | 61 | 409 | 362 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 43 | 483 | 40 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 9 | 484 | 2 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 21 | 484 | 13 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 36 | 484 | 1 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 48 | 484 | 38 | 478 | catalytic, putative [Ricinus communis] |