| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_007156m |
| Family | GT47 |
| Protein Properties | Length: 464 Molecular Weight: 53647.6 Isoelectric Point: 9.9626 |
| Chromosome | Chromosome/Scaffold: 08316 Start: 436325 End: 438331 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 108 | 407 | 0 |
| KDLKIYIYELPAKYNTDWLANERCSNHLFASEAAIHRAISNSDVRTFDPYEADFFFVPVYVSCNFSTVNGFPAIGHARSLISSAVNLVSTNFPFWNRSQG ADHVFVASHDFGSCFHTLEERAMEDGIPKFLKNSIILQTFGVKYRHPCQDVENVVIPPYISPESVQLTLQKTPLTGRRDIWVFFRGKMEVHPKNVSGRFY SKKVRTEIWRKFNGDRRFYLQRHRFAGYQSEIGRSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIQLPFPAAVPWPEISLTVAENNVAKLAKILEHV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 464 Download |
| MGEMLEYKRP PTKRNNRGFY VRMKLVHRHG RFQLHQEKNS NLFFKYYKWI IWISLSIYFF 60 SSYFITHKPI PLYKAQYFSK SSVVSRLLFE STNSTFPQQQ NNNRALLKDL KIYIYELPAK 120 YNTDWLANER CSNHLFASEA AIHRAISNSD VRTFDPYEAD FFFVPVYVSC NFSTVNGFPA 180 IGHARSLISS AVNLVSTNFP FWNRSQGADH VFVASHDFGS CFHTLEERAM EDGIPKFLKN 240 SIILQTFGVK YRHPCQDVEN VVIPPYISPE SVQLTLQKTP LTGRRDIWVF FRGKMEVHPK 300 NVSGRFYSKK VRTEIWRKFN GDRRFYLQRH RFAGYQSEIG RSVFCLCPLG WAPWSPRLVE 360 SVALGCVPVI IADGIQLPFP AAVPWPEISL TVAENNVAKL AKILEHVAAT NLSTIQKNLW 420 DPAVRRALLF NDEMEEGDAT WQVLYALAQK LDRSRRTTRV AVQ* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-74 | 108 | 404 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33322.1 | 0 | 23 | 461 | 1 | 440 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| GenBank | ABI64067.1 | 0 | 23 | 463 | 1 | 442 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
| RefSeq | XP_002275679.1 | 0 | 4 | 452 | 1 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314302.1 | 0 | 4 | 463 | 2 | 462 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523710.1 | 0 | 1 | 463 | 1 | 461 | transferase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
