| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_007677m |
| Family | GT47 |
| Protein Properties | Length: 446 Molecular Weight: 51143.8 Isoelectric Point: 8.1203 |
| Chromosome | Chromosome/Scaffold: 07035 Start: 883401 End: 884964 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 31 | 385 | 0 |
| CTGRWIHIRRLPSRFNLDLLTNCSQYPLFDNFCPYLTNHGLGPKTHNRSQSWYRSDPLLLEVIFHRRMLEYPCLTADPNLANAVYLPYYAAIDALRYLYG PDVNTSMEHGLELFNFLQENDARIWARRKGIDHFLVMARPAWDFSQSLAVDPPVWGTSFLELKEFYNVTALVVEGRAWPWQEQAVPYLTSFHPPTLALFD SWIKRVKSSRRTTLMLFAGGGGAGAGLNIRRSIRHECENNSHSASFLASGGYSSVYYTKVCDLVDCSNGICEHDPIRYMRPMLQATFCLQPPGDTPTRRS TFDAIVAGCIPVFFEEQSAKMQYRWHLPEETYDDFAVFIAKEEVVYKGLKILDVL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 446 Download |
| MACKSHFFLL LCCFLFISIN STFSLESETD CTGRWIHIRR LPSRFNLDLL TNCSQYPLFD 60 NFCPYLTNHG LGPKTHNRSQ SWYRSDPLLL EVIFHRRMLE YPCLTADPNL ANAVYLPYYA 120 AIDALRYLYG PDVNTSMEHG LELFNFLQEN DARIWARRKG IDHFLVMARP AWDFSQSLAV 180 DPPVWGTSFL ELKEFYNVTA LVVEGRAWPW QEQAVPYLTS FHPPTLALFD SWIKRVKSSR 240 RTTLMLFAGG GGAGAGLNIR RSIRHECENN SHSASFLASG GYSSVYYTKV CDLVDCSNGI 300 CEHDPIRYMR PMLQATFCLQ PPGDTPTRRS TFDAIVAGCI PVFFEEQSAK MQYRWHLPEE 360 TYDDFAVFIA KEEVVYKGLK ILDVLMGIPR DQVRRMREKV IELMPRVVYR KHGSSLGLRT 420 KKDAFDIAIE GALERINSRL KSGRF* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-47 | 31 | 375 | 357 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_193989.1 | 0 | 28 | 440 | 34 | 435 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002267390.1 | 0 | 30 | 441 | 32 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002304426.1 | 0 | 19 | 440 | 17 | 429 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002329867.1 | 0 | 1 | 445 | 1 | 437 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002529790.1 | 0 | 1 | 443 | 1 | 452 | catalytic, putative [Ricinus communis] |
