| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_007754m |
| Family | GT30 |
| Protein Properties | Length: 443 Molecular Weight: 49159.6 Isoelectric Point: 9.4731 |
| Chromosome | Chromosome/Scaffold: 06550 Start: 164088 End: 169064 |
| Description | KDO transferase A |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT30 | 43 | 223 | 0 |
| RWPERLGRSSLPRPSGPLIWFHAVSLGEGMAAIPVIKRCVHCRPDLSILMTTTTFSAFEVITNQLPSGVLYQFSPVDTPTAVDAFLDHWKPNAIILLESE LWPNLIMGSSRKRISLALLNARLSMKSFRLWSQPVLLPLISLMLSQFSLIVPLSTMQAIRFQVLQAPPFIINFSGDLKYAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 443 Download |
| MVAAGNTGMI LYKIYRALTY GLTPLVHLHL LWRRRRGLEH PTRWPERLGR SSLPRPSGPL 60 IWFHAVSLGE GMAAIPVIKR CVHCRPDLSI LMTTTTFSAF EVITNQLPSG VLYQFSPVDT 120 PTAVDAFLDH WKPNAIILLE SELWPNLIMG SSRKRISLAL LNARLSMKSF RLWSQPVLLP 180 LISLMLSQFS LIVPLSTMQA IRFQVLQAPP FIINFSGDLK YAVEFDASSG EIGSIEYLKG 240 QLASRHVWMA SSIHRGEEKV MLGVHRALIQ MYPDLVTIIV PRYPQDALEI AQELQKEGLN 300 VALRSQHRRI MPGTQIYMVD TLGELRCLYS LSAVAVIGGS FFPGLAGHNI SEAAAAGCAV 360 LTGHHVGHFS HMVKEMQRLN PLSITQVSGT LELEEAIKEL LNDAKLLDAR RMAAKQAFHA 420 LSSGIIANVW NLLNFHVLEI SS* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04413 | Glycos_transf_N | 7.0e-57 | 41 | 224 | 186 | + 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase). Members of this family transfer activated sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. Members of the family transfer UDP, ADP, GDP or CMP linked sugars. The Glycos_transf_N region is flanked at the N-terminus by a signal peptide and at the C-terminus by Glycos_transf_1 (pfam00534). The eukaryotic glycogen synthases may be distant members of this bacterial family. | ||
| COG1519 | KdtA | 2.0e-98 | 15 | 437 | 426 | + 3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane] | ||
| PRK05749 | PRK05749 | 6.0e-105 | 14 | 420 | 409 | + 3-deoxy-D-manno-octulosonic-acid transferase; Reviewed | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005529 | Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates." [CHEBI:16646, GOC:mah] |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016740 | transferase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABE80128.2 | 0 | 6 | 418 | 2 | 415 | Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal [Medicago truncatula] |
| EMBL | CBI30224.1 | 0 | 5 | 386 | 3 | 385 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002277784.1 | 0 | 5 | 438 | 3 | 436 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002322900.1 | 0 | 1 | 439 | 1 | 439 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528642.1 | 0 | 3 | 439 | 5 | 441 | 3-deoxy-d-manno-octulosonic-acid transferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2xcu_D | 6e-22 | 50 | 405 | 33 | 348 | A Chain A, Crystal Structure Of Human Glcat-P Apo Form |
| PDB | 2xcu_C | 6e-22 | 50 | 405 | 33 | 348 | A Chain A, Crystal Structure Of Human Glcat-P Apo Form |
| PDB | 2xcu_B | 6e-22 | 50 | 405 | 33 | 348 | A Chain A, Crystal Structure Of Human Glcat-P Apo Form |
| PDB | 2xcu_A | 6e-22 | 50 | 405 | 33 | 348 | A Chain A, Crystal Structure Of Human Glcat-P Apo Form |
| PDB | 2xci_D | 6e-22 | 50 | 405 | 33 | 348 | A Chain A, Membrane-Embedded Monofunctional Glycosyltransferase Waaa Of Aquifex Aeolicus, Substrate-Free Form |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| KDO transfer to lipid IVA I | KDOTRANS-RXN | EC-2.4.99.12 | lipid IVA 3-deoxy-D-manno-octulosonic acid transferase |
| KDO transfer to lipid IVA I | KDOTRANS2-RXN | EC-2.4.99.13 | (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY279419 | 385 | 41 | 424 | 0 |
| DY266328 | 360 | 10 | 369 | 0 |
| FC917851 | 301 | 41 | 341 | 0 |
| DY288817 | 353 | 10 | 361 | 0 |
| FC901247 | 305 | 10 | 314 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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