| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_007875m |
| Family | GH29 |
| Protein Properties | Length: 439 Molecular Weight: 50009 Isoelectric Point: 8.8582 |
| Chromosome | Chromosome/Scaffold: 00341 Start: 1078363 End: 1080107 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH29 | 42 | 311 | 0 |
| QLKWQQRELIMFFHFGVNTFTDSEWGTGHENPAIFNPVGLNAKQWVDTAAEAAVSLVILTAKHHDGFCLWPSKYTRHSVASSPWKNGHGDVVQELVNAAK NHGGVDVGLYLSPWDRHDRRYGHNLPYNEYYLAQLQELLSKYGDVREIWFDGAKGSNAPNMSYYFSSWFAMVKELQSSINIFSDAGPDVRWVDNENGFAG TTSWSTINRTSLSIGNGSIMDYLNTGDPKGTDWLPAECDVSIRKGWFWHKSESPKKLSKLLDIYYKSVEK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 439 Download |
| MAKLWCFLCI ITFIQLFKFV ISKRELLPTP PLPILPLPSF SQLKWQQREL IMFFHFGVNT 60 FTDSEWGTGH ENPAIFNPVG LNAKQWVDTA AEAAVSLVIL TAKHHDGFCL WPSKYTRHSV 120 ASSPWKNGHG DVVQELVNAA KNHGGVDVGL YLSPWDRHDR RYGHNLPYNE YYLAQLQELL 180 SKYGDVREIW FDGAKGSNAP NMSYYFSSWF AMVKELQSSI NIFSDAGPDV RWVDNENGFA 240 GTTSWSTINR TSLSIGNGSI MDYLNTGDPK GTDWLPAECD VSIRKGWFWH KSESPKKLSK 300 LLDIYYKSVE KCSIKASSQR GGKDGDFGPE NVIDRDHLRT YWVPRDEEKE GSWIEIRCNE 360 GLRFNVIRIQ EAIGLGQRIK RHEIYVDGKK VGKGTTVGYK RLHKLEEKVV KGQIVRIKFL 420 KSREVPVISS IGLHYDPF* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 4.0e-22 | 76 | 240 | 178 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 6.0e-24 | 45 | 193 | 186 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 9.0e-39 | 42 | 277 | 264 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 41 | 438 | 22 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 25 | 438 | 3 | 458 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 438 | 1 | 479 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 438 | 1 | 480 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 438 | 1 | 480 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3mo4_B | 0 | 38 | 429 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 38 | 429 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 38 | 429 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 38 | 429 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3uet_B | 0 | 38 | 429 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
