| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_007928m |
| Family | GT47 |
| Protein Properties | Length: 437 Molecular Weight: 50878.1 Isoelectric Point: 8.1758 |
| Chromosome | Chromosome/Scaffold: 02960 Start: 141891 End: 143397 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 10 | 356 | 0 |
| CLGRYIYIHRLPKRFNQELLDNCGSITVGTEHNMCPYLVNYALGHEVENSQGILLNKSWYSTNQFLLEVIFHYRMKKYKCLTNDSSRASAIYIPFYAGLD VSGYLWGVKTSVRDQSAFDLVKWLVEKPEWKKMLGRDHFLVAGRISWDFRRQTDNESDWGSKFRFLPESNNMSMLAIESSSWNNDYAIPYPTCFHPSKDS EVLQWQDKMRRQKRPYLFSFAGAPRPDLQESVRGKIIEECLASKNLCKLLECDYGVNGAINCDNPANVMKLFQNSVYCLQPTGDSYTRRSIFDSILAGCI PVFFHPGTAYAQYKWHLPKNYSKYSVYIPVRDVKDWKTGINETLLRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 437 Download |
| MKTDYHKDSC LGRYIYIHRL PKRFNQELLD NCGSITVGTE HNMCPYLVNY ALGHEVENSQ 60 GILLNKSWYS TNQFLLEVIF HYRMKKYKCL TNDSSRASAI YIPFYAGLDV SGYLWGVKTS 120 VRDQSAFDLV KWLVEKPEWK KMLGRDHFLV AGRISWDFRR QTDNESDWGS KFRFLPESNN 180 MSMLAIESSS WNNDYAIPYP TCFHPSKDSE VLQWQDKMRR QKRPYLFSFA GAPRPDLQES 240 VRGKIIEECL ASKNLCKLLE CDYGVNGAIN CDNPANVMKL FQNSVYCLQP TGDSYTRRSI 300 FDSILAGCIP VFFHPGTAYA QYKWHLPKNY SKYSVYIPVR DVKDWKTGIN ETLLRIPQDR 360 VMAMREEVIK LIPRIIYADP RSRLETFEDA FDLAVKGILE RIERVRWEIK ERKDPSIGFA 420 EGDDYKYTFS GYVGEE* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-68 | 9 | 356 | 363 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_193135.2 | 0 | 9 | 432 | 94 | 514 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002300146.1 | 0 | 8 | 435 | 106 | 518 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002321098.1 | 0 | 2 | 436 | 42 | 472 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002518609.1 | 0 | 6 | 421 | 72 | 482 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| RefSeq | XP_002532518.1 | 0 | 7 | 435 | 99 | 527 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FF380105 | 253 | 116 | 368 | 0 |
| ES802449 | 295 | 138 | 432 | 0 |
| DV145943 | 263 | 62 | 324 | 0 |
| EY661612 | 260 | 146 | 405 | 0 |
| CV273928 | 237 | 201 | 437 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
