| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_007991m |
| Family | GT47 |
| Protein Properties | Length: 434 Molecular Weight: 50515.1 Isoelectric Point: 9.5166 |
| Chromosome | Chromosome/Scaffold: 04175 Start: 808147 End: 811555 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 52 | 366 | 0 |
| RLKVYMYELPRRFHVGMMDHKSKIDDDVPVTADNLPRWPKNVGIKKQHSVEYWLMASLLYDGGKEEREVVRVLDPEAADAFFVPFFSSLSFNTHGHNMTD PETEKDRQLQVALIEFLYKSKYWQRSGGRDHVIPMTHPNAFRFLRQQLNASILIVADFGRYPKSMSTLRKDVVAPYVHVVDSFTDDEISDPFESRTTLLF FRGNTVRKDEGRVRAKLEKILASYDDVHFERSTPTTQTIKVSTQGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDQIELPYEDEIDYSQFSIFFS VNEAIQPGFIINQLR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 434 Download |
| MYGKVIFSIG FIFLLVFSYS IFIGTLDFRS YFLPGLQQLP IGAVSVCATG PRLKVYMYEL 60 PRRFHVGMMD HKSKIDDDVP VTADNLPRWP KNVGIKKQHS VEYWLMASLL YDGGKEEREV 120 VRVLDPEAAD AFFVPFFSSL SFNTHGHNMT DPETEKDRQL QVALIEFLYK SKYWQRSGGR 180 DHVIPMTHPN AFRFLRQQLN ASILIVADFG RYPKSMSTLR KDVVAPYVHV VDSFTDDEIS 240 DPFESRTTLL FFRGNTVRKD EGRVRAKLEK ILASYDDVHF ERSTPTTQTI KVSTQGMRSS 300 KFCLHPAGDT PSSCRLFDAI VSHCVPVIVS DQIELPYEDE IDYSQFSIFF SVNEAIQPGF 360 IINQLRQFPK DRWIKMWRQL KNISHHFEFQ YPPKKEDAID MLWRQVKHKL PSVKLSVHRS 420 RRLKVPDWWQ RRR* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-72 | 51 | 368 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18793.1 | 0 | 1 | 410 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
| RefSeq | NP_176908.2 | 0 | 1 | 429 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002272591.1 | 0 | 27 | 433 | 27 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311068.1 | 0 | 53 | 429 | 2 | 380 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002512333.1 | 0 | 1 | 432 | 1 | 434 | catalytic, putative [Ricinus communis] |
