| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_008638m |
| Family | GT47 |
| Protein Properties | Length: 414 Molecular Weight: 47342.7 Isoelectric Point: 7.2345 |
| Chromosome | Chromosome/Scaffold: 10316 Start: 29593 End: 32838 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 46 | 341 | 0 |
| RLKVYVYELPSKYNKKLLQKDPRCLTYMFAAEIFIHRFLLSSAVRTLNPDEADWFYTPIYTTCDLTPTGMPLPFKSPRMMRSAIQLISTNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIKRGILPLLQRATLVQTFGQRNHVCLNEGSITIPPYAPPQKMQARQIPPETPRSIFVYFRGLFYDVNNDPEGGYYARGA RAAVWENFKNNPLFDISTEHPTTYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEQIGVFVAEEDVPNLDMILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 414 Download |
| MRVSMWFLVL LLVFGFNDRS FAHQRPRTER ISGSAGDVLE DDPVGRLKVY VYELPSKYNK 60 KLLQKDPRCL TYMFAAEIFI HRFLLSSAVR TLNPDEADWF YTPIYTTCDL TPTGMPLPFK 120 SPRMMRSAIQ LISTNWPYWN RTEGADHFFV VPHDFGACFH YQEEKAIKRG ILPLLQRATL 180 VQTFGQRNHV CLNEGSITIP PYAPPQKMQA RQIPPETPRS IFVYFRGLFY DVNNDPEGGY 240 YARGARAAVW ENFKNNPLFD ISTEHPTTYY EDMQRAIFCL CPLGWAPWSP RLVEAVVFGC 300 IPVIIADDIV LPFADAIPWE QIGVFVAEED VPNLDMILTS IPTEEILRKQ RLLANPSMKR 360 AMLFPQPAQS GDAFHQILNG LARKLPHDEK IFLKPGEKVL NWTAGPVGDL KPW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-79 | 46 | 341 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33320.1 | 0 | 1 | 413 | 1 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_174064.1 | 0 | 8 | 413 | 7 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002297880.1 | 0 | 1 | 413 | 1 | 412 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002304637.1 | 0 | 1 | 413 | 1 | 413 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 1 | 413 | 1 | 417 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
