| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_009619m |
| Family | GT57 |
| Protein Properties | Length: 383 Molecular Weight: 44130.8 Isoelectric Point: 9.6732 |
| Chromosome | Chromosome/Scaffold: 06871 Start: 537140 End: 542932 |
| Description | ALG6, ALG8 glycosyltransferase family |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT57 | 1 | 360 | 0 |
| MRWTVLSSDALIFFPAVLYFVLVYYRNHSSRRKSDVAWHIAMILINPCLILVDHGHFQYNCISLGLTVGAIAAVLSHKDLVASVLFCLSLNHKQMSAYFA PAFFSHLLGKCLKHKNPVLEVSKLGLVVLGTFTIIWWPYLNSRDTVMEVLFRLAPFERGIYEDYVANFWCTTSILIKWKRLFTTQSLKFVSLLATVLTFL PSMVQQIMAPSRKGFLYALVNSSFSFYLFSFQVHEKSILLPLLPASLLATELRGPFELLMHYALFSMFPLLCRDKLIVPYVALYALFFLLYFTPSGRKDA KIHNSTTLTCLSILLTFLYLCSLLLHILYLIIHPPKKYPFLFEAMIMLLCFSHFILFVSY | |||
| Full Sequence |
|---|
| Protein Sequence Length: 383 Download |
| MRWTVLSSDA LIFFPAVLYF VLVYYRNHSS RRKSDVAWHI AMILINPCLI LVDHGHFQYN 60 CISLGLTVGA IAAVLSHKDL VASVLFCLSL NHKQMSAYFA PAFFSHLLGK CLKHKNPVLE 120 VSKLGLVVLG TFTIIWWPYL NSRDTVMEVL FRLAPFERGI YEDYVANFWC TTSILIKWKR 180 LFTTQSLKFV SLLATVLTFL PSMVQQIMAP SRKGFLYALV NSSFSFYLFS FQVHEKSILL 240 PLLPASLLAT ELRGPFELLM HYALFSMFPL LCRDKLIVPY VALYALFFLL YFTPSGRKDA 300 KIHNSTTLTC LSILLTFLYL CSLLLHILYL IIHPPKKYPF LFEAMIMLLC FSHFILFVSY 360 TNAQQWMLSR PYTLKDKEKK LN* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03155 | Alg6_Alg8 | 6.0e-70 | 1 | 363 | 371 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001145139.1 | 0 | 1 | 369 | 138 | 507 | hypothetical protein LOC100278369 [Zea mays] |
| RefSeq | NP_198662.1 | 0 | 1 | 380 | 147 | 531 | ALG6, ALG8 glycosyltransferase family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280181.1 | 0 | 1 | 381 | 138 | 515 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002305159.1 | 0 | 1 | 382 | 109 | 491 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002329281.1 | 0 | 1 | 381 | 105 | 485 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5470 | EC-2.4.1.267 | Dol-P-Glc:Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |
