| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_010258m |
| Family | GT4 |
| Protein Properties | Length: 365 Molecular Weight: 41615.1 Isoelectric Point: 9.0737 |
| Chromosome | Chromosome/Scaffold: 00435 Start: 87832 End: 91455 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT4 | 166 | 328 | 8.2e-25 |
| PATTPIFISVAQFRPEKAHPLQLEAFSVAIRKLDPDLPRPKLQFVGSCRHKSDEERLQKLKDKAVELKVDGDVQFYKNVMYRELISLLGGAIAGMHSMTD EHFGISVVEYMAAGAIPIAHNSAGPKMDIVLEEDGQQTGFLAQTVEEYADAILRVLRMPETER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 365 Download |
| MVVHLYKRKW VEENSYPRFT MIGQSLGSIY LSWEALCKFT PSFYFDTSGY AFTYPLARIF 60 GCKVICYTHY PTISLDMISR VRSRNSMYNN DASIARSGWL SQCKIIYYTF FSWMYGFAGS 120 CAHLAMVNSS WTQSHIEKLW KIPKCIRRVY PPCDTSGLQA LPLERPATTP IFISVAQFRP 180 EKAHPLQLEA FSVAIRKLDP DLPRPKLQFV GSCRHKSDEE RLQKLKDKAV ELKVDGDVQF 240 YKNVMYRELI SLLGGAIAGM HSMTDEHFGI SVVEYMAAGA IPIAHNSAGP KMDIVLEEDG 300 QQTGFLAQTV EEYADAILRV LRMPETERLK MAAAARKRAS RFSEQRFYED FKAAVRLVLN 360 HDSK* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0438 | RfaG | 4.0e-21 | 106 | 360 | 259 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| pfam00534 | Glycos_transf_1 | 4.0e-22 | 168 | 328 | 163 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. | ||
| cd03805 | GT1_ALG2_like | 2.0e-27 | 10 | 331 | 337 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
| cd03806 | GT1_ALG11_like | 1.0e-172 | 2 | 350 | 352 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. | ||
| PLN02949 | PLN02949 | 0 | 1 | 364 | 364 | + transferase, transferring glycosyl groups | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA99697.1 | 0 | 2 | 360 | 97 | 455 | glycosyl transferase, group 1 family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| GenBank | EAZ21019.1 | 0 | 2 | 360 | 53 | 411 | hypothetical protein OsJ_36668 [Oryza sativa Japonica Group] |
| RefSeq | NP_181548.2 | 0 | 2 | 360 | 101 | 459 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | XP_002318120.1 | 0 | 2 | 364 | 104 | 466 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528312.1 | 0 | 1 | 364 | 102 | 465 | glycosyl transferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2f9f_A | 0.00000003 | 172 | 342 | 26 | 177 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
| PDB | 2xa1_B | 0.000001 | 170 | 341 | 232 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2xa1_A | 0.000001 | 170 | 341 | 232 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2x6r_B | 0.000001 | 170 | 341 | 232 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| PDB | 2x6r_A | 0.000001 | 170 | 341 | 232 | 396 | A Chain A, Crystal Structure Of Trehalose Synthase Tret From P. Horikoshii (Seleno Derivative) |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5464 | EC-2.4.1.131 | GDP-Man:Man3GlcNAc2-PP-Dol α-1,2-mannosyltransferase |
