| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_011475m |
| Family | CE10 |
| Protein Properties | Length: 335 Molecular Weight: 37573.1 Isoelectric Point: 9.5643 |
| Chromosome | Chromosome/Scaffold: 08744 Start: 89678 End: 90814 |
| Description | carboxyesterase 18 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 47 | 331 | 0 |
| IRTCPSKKPKNGVKTTDITVDKARNLWFRLYTPTKTGDGTAASGLPVIFYFHGGGFAFLAPSSLPYDKFCRRLASELSAIIISVNYRLAPEHRCPSQYED GLDTLKFIDTTKIKGFSGNLKQCFIAGDSAGGNLVHHVAVKASEHEFSNLKLIGNILIQPFFGGEERTESELRLTRAPLVNMERADWMWKAFLPEGSNRD HPAANVFGPNSVDISGVKLPATIIFVGGFDPLQDWQKRYYKGLKKSGKEASLVELANAFHSFYNYPQLPEFSSLMKEMKNFMQKQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 335 Download |
| MAQNDVPQWP DLPFTVKLSI LAFSFVFDIT RNRNGTANRF LMSFFDIRTC PSKKPKNGVK 60 TTDITVDKAR NLWFRLYTPT KTGDGTAASG LPVIFYFHGG GFAFLAPSSL PYDKFCRRLA 120 SELSAIIISV NYRLAPEHRC PSQYEDGLDT LKFIDTTKIK GFSGNLKQCF IAGDSAGGNL 180 VHHVAVKASE HEFSNLKLIG NILIQPFFGG EERTESELRL TRAPLVNMER ADWMWKAFLP 240 EGSNRDHPAA NVFGPNSVDI SGVKLPATII FVGGFDPLQD WQKRYYKGLK KSGKEASLVE 300 LANAFHSFYN YPQLPEFSSL MKEMKNFMQK QLDK* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00135 | COesterase | 5.0e-8 | 77 | 193 | 130 | + Carboxylesterase family. | ||
| cd00312 | Esterase_lipase | 7.0e-9 | 76 | 193 | 129 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| PRK10162 | PRK10162 | 1.0e-17 | 75 | 311 | 240 | + acetyl esterase; Provisional | ||
| COG0657 | Aes | 1.0e-36 | 53 | 332 | 281 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 2.0e-64 | 94 | 310 | 217 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76040.1 | 0 | 10 | 328 | 13 | 327 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268777.1 | 0 | 10 | 331 | 4 | 320 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268861.1 | 0 | 10 | 328 | 13 | 327 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002523490.1 | 0 | 8 | 331 | 7 | 331 | Arylacetamide deacetylase, putative [Ricinus communis] |
| RefSeq | XP_002528343.1 | 0 | 11 | 332 | 9 | 329 | Arylacetamide deacetylase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2zsi_A | 0 | 12 | 331 | 23 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 2zsh_A | 0 | 12 | 331 | 23 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 3ed1_F | 0 | 12 | 332 | 15 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 3ed1_E | 0 | 12 | 332 | 15 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 3ed1_D | 0 | 12 | 332 | 15 | 351 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FF380509 | 277 | 10 | 286 | 0 |
| DY269018 | 330 | 12 | 334 | 0 |
| DY262759 | 314 | 7 | 318 | 0 |
| FC908024 | 312 | 12 | 316 | 0 |
| DY291484 | 303 | 34 | 334 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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