| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_011607m |
| Family | GT47 |
| Protein Properties | Length: 331 Molecular Weight: 37881.1 Isoelectric Point: 9.0559 |
| Chromosome | Chromosome/Scaffold: 09876 Start: 772451 End: 775752 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 50 | 261 | 5.60519e-44 |
| RLKVFVYELPSKYNKKVLQKDPRCLTHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFAACFHYLEEKAIERGILHLLQRATLVQTFGQRNHVCLKEGSIIVPPYAPPQKMQAHFIPEKTPRSIFVYFRGLFYDVGNDPEGGYYARYV LEQQCGKTSRTI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 331 Download |
| MEIWKWVFVG ILCFAAFAST AGAVKLGRGQ PTERISGSAG DVLEDDPVGR LKVFVYELPS 60 KYNKKVLQKD PRCLTHMFAA EIFMHRFLLS SPVRTLNPEE ADWFYTPVYT TCDLTPNGLP 120 LPFKSPRMMR SAIQLISSNW PYWNRTEGAD HFFVVPHDFA ACFHYLEEKA IERGILHLLQ 180 RATLVQTFGQ RNHVCLKEGS IIVPPYAPPQ KMQAHFIPEK TPRSIFVYFR GLFYDVGNDP 240 EGGYYARYVL EQQCGKTSRT IHFLTYPQIT QLHTTKTCNE PCFACVRLAG LHGVRDWLKL 300 LSLVAFRLSL QMTLCYLLRM QFHGKKLGFL * 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-43 | 50 | 278 | 240 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM64940.1 | 0 | 1 | 247 | 1 | 245 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_568941.1 | 0 | 1 | 247 | 1 | 245 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002284685.1 | 0 | 1 | 247 | 1 | 246 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318180.1 | 0 | 1 | 247 | 1 | 247 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 1 | 247 | 1 | 247 | catalytic, putative [Ricinus communis] |
