| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_011906m |
| Family | GH47 |
| Protein Properties | Length: 323 Molecular Weight: 36218.8 Isoelectric Point: 5.423 |
| Chromosome | Chromosome/Scaffold: 05618 Start: 112196 End: 117398 |
| Description | alpha-mannosidase 2 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH47 | 114 | 321 | 0 |
| AMLHAWTCYEKYAWGHDELQPQTRNGIDSFGGLGATLVDSLDTLFIMGLHEQFQRARDWIANSLDFNKNYDASVFETSIRVVGGLLSAYDLSGDKIFLDK ARDIADRLLPAWNTPSGIPYNTINLAQGNPHNPGWTGGNSILADSATEQLEFIALSQRTKEPKYQQKVENVIRELHKNFPADGLLPIYINPHTGMSTHSV ITFGAMGD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 323 Download |
| MGKKSSSSSS SVLLSNSKNK NVWIRSNRFV LLIIGFVLLT CFFLDRQSLA RDHQVEVSIL 60 NEELSDLRSQ LEDLTTQLKD SGIDIPISDT KRKMKEEEED DPISVERREK VKEAMLHAWT 120 CYEKYAWGHD ELQPQTRNGI DSFGGLGATL VDSLDTLFIM GLHEQFQRAR DWIANSLDFN 180 KNYDASVFET SIRVVGGLLS AYDLSGDKIF LDKARDIADR LLPAWNTPSG IPYNTINLAQ 240 GNPHNPGWTG GNSILADSAT EQLEFIALSQ RTKEPKYQQK VENVIRELHK NFPADGLLPI 300 YINPHTGMST HSVITFGAMG DR* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04156 | IncA | 0.0003 | 30 | 170 | 144 | + IncA protein. Chlamydia trachomatis is an obligate intracellular bacterium that develops within a parasitophorous vacuole termed an inclusion. The inclusion is non-fusogenic with lysosomes but intercepts lipids from a host cell exocytic pathway. Initiation of chlamydial development is concurrent with modification of the inclusion membrane by a set of C. trachomatis-encoded proteins collectively designated Incs. One of these Incs, IncA, is functionally associated with the homotypic fusion of inclusions. This family probably includes members of the wider Inc family rather than just IncA. | ||
| PTZ00470 | PTZ00470 | 9.0e-95 | 95 | 321 | 230 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 4.0e-102 | 114 | 321 | 211 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI17906.1 | 0 | 23 | 321 | 46 | 344 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI18472.1 | 0 | 25 | 321 | 22 | 317 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002310939.1 | 0 | 25 | 321 | 24 | 313 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325257.1 | 0 | 1 | 321 | 1 | 314 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519409.1 | 0 | 1 | 321 | 1 | 304 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1fmi_A | 0 | 102 | 321 | 4 | 224 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 102 | 321 | 4 | 224 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 102 | 321 | 4 | 224 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 36 | 321 | 2 | 302 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| PDB | 1nxc_A | 0 | 94 | 321 | 7 | 238 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
