| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_011942m |
| Family | GH19 |
| Protein Properties | Length: 322 Molecular Weight: 35183.7 Isoelectric Point: 6.9602 |
| Chromosome | Chromosome/Scaffold: 01551 Start: 3124922 End: 3126578 |
| Description | chitinase-like protein 2 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 62 | 304 | 0 |
| SDYFQTYQFENLFAKRNTPVAHAVGFWDYHSFITAAAVYQPHGFGTTGGKLTGQKEVAAFLGHVGSKTSCGYGVATGGPLAWGLCYNKEMSPSQSYCDDY YKYTYPCTPGVSYHGRGALPIYWNYNYGKAGEALKIDLLNHPEYIENNATLAFQAAIWKWMTPEKKNQPSAHDVFVGNWKPTKNDTLSKRVPGFGITMNV LYGDQVCGKGDDESMNNIVSHYLYYLDLLGVGREEAGPHEVLS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 322 Download |
| MEARNCVLAT MALLILVVAV NGGDDQPSSV KPLVKIVKGK KVCDKGWECK GLSAYCCNDT 60 ISDYFQTYQF ENLFAKRNTP VAHAVGFWDY HSFITAAAVY QPHGFGTTGG KLTGQKEVAA 120 FLGHVGSKTS CGYGVATGGP LAWGLCYNKE MSPSQSYCDD YYKYTYPCTP GVSYHGRGAL 180 PIYWNYNYGK AGEALKIDLL NHPEYIENNA TLAFQAAIWK WMTPEKKNQP SAHDVFVGNW 240 KPTKNDTLSK RVPGFGITMN VLYGDQVCGK GDDESMNNIV SHYLYYLDLL GVGREEAGPH 300 EVLSCAEQVP FNQASSSSSS S* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-68 | 69 | 293 | 225 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 6.0e-99 | 65 | 305 | 241 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAQ56598.1 | 0 | 1 | 312 | 1 | 306 | chitinase-like protein [Gossypium hirsutum] |
| GenBank | AAQ56599.1 | 0 | 1 | 321 | 1 | 316 | chitinase-like protein [Gossypium hirsutum] |
| GenBank | ABL86685.1 | 0 | 1 | 312 | 1 | 305 | CLT3 [Gossypium barbadense] |
| RefSeq | XP_002316022.1 | 0 | 1 | 313 | 1 | 312 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519197.1 | 0 | 17 | 321 | 19 | 324 | chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3cql_B | 0 | 61 | 311 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 61 | 311 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3w3e_B | 0 | 70 | 311 | 12 | 241 | A Chain A, Structure Of Vigna Unguiculata Chitinase With Regulation Activity Of The Plant Cell Wall |
| PDB | 3w3e_A | 0 | 70 | 311 | 12 | 241 | A Chain A, Structure Of Vigna Unguiculata Chitinase With Regulation Activity Of The Plant Cell Wall |
| PDB | 1dxj_A | 0 | 70 | 311 | 11 | 240 | A Chain A, Structure Of The Chitinase From Jack Bean |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
