| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_012214m |
| Family | GH89 |
| Protein Properties | Length: 315 Molecular Weight: 36886.5 Isoelectric Point: 6.6797 |
| Chromosome | Chromosome/Scaffold: 04083 Start: 453894 End: 456102 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH89 | 9 | 303 | 0 |
| DAWIDLYSTRRYGRSDPLVQDAWNILYHTVYNCTDGAYDKNRDVIVAFPDVDPFFILASHKKYHHNGKPVSRRAVLKENSDSYDHPHLWYSTSEVIRALE FLIKGGEELSGSSTYSYDLVDLTRQALAKYANELFLKIIESYQSNDVNGVANLSQKFLNLVEDMDTLLACHKGFLLGPWLESAKQLAKDKEQERQFEWNA RTQITMWFDNTEDKASLLRDYGNKYWSGLLIDYYGPRAAIYFKYLISSLENGHGFPLKEWRREWIKLTNNWQKSRNNFPVESNGNPLIISRWLYE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 315 Download |
| MKNLFHCIDA WIDLYSTRRY GRSDPLVQDA WNILYHTVYN CTDGAYDKNR DVIVAFPDVD 60 PFFILASHKK YHHNGKPVSR RAVLKENSDS YDHPHLWYST SEVIRALEFL IKGGEELSGS 120 STYSYDLVDL TRQALAKYAN ELFLKIIESY QSNDVNGVAN LSQKFLNLVE DMDTLLACHK 180 GFLLGPWLES AKQLAKDKEQ ERQFEWNART QITMWFDNTE DKASLLRDYG NKYWSGLLID 240 YYGPRAAIYF KYLISSLENG HGFPLKEWRR EWIKLTNNWQ KSRNNFPVES NGNPLIISRW 300 LYEKYLHSPD TYDQ* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12972 | NAGLU_C | 4.0e-99 | 10 | 305 | 296 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI15090.1 | 0 | 8 | 313 | 536 | 845 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001054095.1 | 0 | 8 | 310 | 207 | 513 | Os04g0650900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002280399.1 | 0 | 8 | 313 | 503 | 812 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318632.1 | 0 | 8 | 313 | 506 | 811 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511461.1 | 0 | 8 | 311 | 502 | 805 | alpha-n-acetylglucosaminidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 2e-27 | 10 | 305 | 602 | 877 | A Chain A, Crystal Structure Of Chondroitin Polymerase From Escherichia Coli Strain K4 (K4cp) Complexed With Udp-Glcua And Udp |
| PDB | 2vcb_A | 2e-27 | 10 | 305 | 602 | 877 | A Chain A, Crystal Structure Of Chondroitin Polymerase From Escherichia Coli Strain K4 (K4cp) Complexed With Udp-Glcua And Udp |
| PDB | 2vca_A | 2e-27 | 10 | 305 | 602 | 877 | A Chain A, Crystal Structure Of Chondroitin Polymerase From Escherichia Coli Strain K4 (K4cp) Complexed With Udp-Glcua And Udp |
| PDB | 2vc9_A | 2e-27 | 10 | 305 | 602 | 877 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 2e-27 | 10 | 305 | 625 | 900 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DR918913 | 281 | 39 | 315 | 0 |
| GT049437 | 295 | 18 | 311 | 0 |
| GT044006 | 295 | 18 | 311 | 0 |
| HO783128 | 265 | 8 | 272 | 0 |
| EY682897 | 228 | 47 | 274 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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