| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_012629m |
| Family | GT47 |
| Protein Properties | Length: 304 Molecular Weight: 35018.2 Isoelectric Point: 9.359 |
| Chromosome | Chromosome/Scaffold: 06688 Start: 166899 End: 169982 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 7 | 226 | 0 |
| DKEINQTYVKVLSQMPYFRRSGGRDHVFVFPSGAGAHLFRSWATYINRSIILTPEGDRTDKKDTSAYNTWKDIIIPGNVEDGMTKRGTTAVQPLPLSKRK YLANYLGRAQGKIGRLKLIDLAKQYPDKLESPELKFSGPDKLGRLEYFQHLRNAKFCLAPRGESSWTLRFYESFFVECVPVILSDQAELPFQNVIDYTYF SIKWPSTQIGHELLDYLESI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 304 Download |
| MMGGLNDKEI NQTYVKVLSQ MPYFRRSGGR DHVFVFPSGA GAHLFRSWAT YINRSIILTP 60 EGDRTDKKDT SAYNTWKDII IPGNVEDGMT KRGTTAVQPL PLSKRKYLAN YLGRAQGKIG 120 RLKLIDLAKQ YPDKLESPEL KFSGPDKLGR LEYFQHLRNA KFCLAPRGES SWTLRFYESF 180 FVECVPVILS DQAELPFQNV IDYTYFSIKW PSTQIGHELL DYLESIPDED VERMIARGRN 240 IRCLWVYAPE SELCSAMQGI MWELQRKVRQ LHQSAETFWL HNRTIVNRNL VGFSSWKPPM 300 PLP* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-29 | 14 | 226 | 218 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM61682.1 | 0 | 1 | 303 | 160 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 1 | 303 | 157 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 303 | 158 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 303 | 158 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 303 | 151 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX668832 | 280 | 1 | 280 | 0 |
| FE707913 | 274 | 31 | 304 | 0 |
| EH692645 | 270 | 7 | 276 | 0 |
| FE707914 | 248 | 1 | 248 | 0 |
| GR005989 | 246 | 37 | 282 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
| Phylogeny |
|---|
 |