| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_013685m |
| Family | GT47 |
| Protein Properties | Length: 276 Molecular Weight: 31569.3 Isoelectric Point: 8.7179 |
| Chromosome | Chromosome/Scaffold: 04182 Start: 439862 End: 441443 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 2 | 220 | 0 |
| SSAVRLISTNFPFWNRSQGADHVFVASHDFGSCFHTLEDKAIEDGVPEFLKNSIILQTFGVNYYHPCQDVENVVIPPYVFPESVRSSLLKAPLTDRRDIW VFFRGKMEVHPKNVSGRFYSRKVRTELWRKFSGDRRFYLQRHRFAGYQSEIVRSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPDAVPWPEI SLTVAERDVAKLGMILEHV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 276 Download |
| MSSAVRLIST NFPFWNRSQG ADHVFVASHD FGSCFHTLED KAIEDGVPEF LKNSIILQTF 60 GVNYYHPCQD VENVVIPPYV FPESVRSSLL KAPLTDRRDI WVFFRGKMEV HPKNVSGRFY 120 SRKVRTELWR KFSGDRRFYL QRHRFAGYQS EIVRSVFCLC PLGWAPWSPR LVESVALGCV 180 PVIIADGIRL PFPDAVPWPE ISLTVAERDV AKLGMILEHV AATNLSAIQK NLWDPAVKRA 240 LLFNNQIEEG DATWHVLYAL AQKLDRSHRT VRVWD* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-52 | 1 | 217 | 221 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33322.1 | 0 | 1 | 273 | 167 | 439 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| GenBank | ABI64067.1 | 0 | 1 | 273 | 167 | 439 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
| RefSeq | XP_002275679.1 | 0 | 1 | 265 | 177 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314302.1 | 0 | 1 | 273 | 187 | 459 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523710.1 | 0 | 1 | 273 | 186 | 458 | transferase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY287013 | 273 | 1 | 273 | 0 |
| HO797103 | 273 | 1 | 273 | 0 |
| CU543526 | 249 | 1 | 249 | 0 |
| EG690266 | 239 | 31 | 269 | 0 |
| GO349198 | 225 | 49 | 273 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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