| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_013738m |
| Family | GH19 |
| Protein Properties | Length: 274 Molecular Weight: 29397.7 Isoelectric Point: 4.2158 |
| Chromosome | Chromosome/Scaffold: 07885 Start: 40011 End: 40990 |
| Description | homolog of carrot EP3-3 chitinase |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 72 | 273 | 0 |
| VADVVTAEFFNGIIDQAEDSCVGKSFYSREVFLDALSSYPRFGRVGSADDSKREIAAFFAHVTHETGHFCFIEEINGASKDYCDEENTQYPCNPDKGYYG RGPIQLSWNFNYGPAGESIGFDGLNSPETVANDPLISFKTALWYWMNNVQSVMSQGFGATIRAINGDLECDGGNSATVQARVGYYTDYCSQLGVAPGENL TC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 274 Download |
| MATLTRKHLA IIVLAGIFAG VLPAYVVAQN CGCAANECCS RWGFCGTTEE YCGTGCQGGP 60 CIPPPPVNDV SVADVVTAEF FNGIIDQAED SCVGKSFYSR EVFLDALSSY PRFGRVGSAD 120 DSKREIAAFF AHVTHETGHF CFIEEINGAS KDYCDEENTQ YPCNPDKGYY GRGPIQLSWN 180 FNYGPAGESI GFDGLNSPET VANDPLISFK TALWYWMNNV QSVMSQGFGA TIRAINGDLE 240 CDGGNSATVQ ARVGYYTDYC SQLGVAPGEN LTC* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00270 | ChtBD1 | 0.0006 | 33 | 51 | 19 | + Chitin binding domain. | ||
| COG3179 | COG3179 | 4.0e-5 | 121 | 216 | 127 | + Predicted chitinase [General function prediction only] | ||
| cd00442 | lysozyme_like | 5.0e-9 | 147 | 231 | 85 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-98 | 75 | 273 | 232 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 1.0e-106 | 76 | 273 | 230 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN79254.1 | 0 | 1 | 273 | 1 | 274 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002274537.1 | 0 | 1 | 273 | 1 | 274 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002274758.1 | 0 | 1 | 273 | 1 | 274 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002326039.1 | 0 | 17 | 273 | 2 | 258 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002330662.1 | 0 | 29 | 273 | 31 | 275 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 71 | 273 | 1 | 204 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3hbe_X | 0 | 71 | 273 | 1 | 204 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3hbd_A | 0 | 71 | 273 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 4dyg_B | 0 | 70 | 273 | 1 | 237 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 4dyg_A | 0 | 70 | 273 | 1 | 237 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
