| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_021028m |
| Family | GT47 |
| Protein Properties | Length: 700 Molecular Weight: 79992.1 Isoelectric Point: 6.5528 |
| Chromosome | Chromosome/Scaffold: 08823 Start: 109037 End: 112317 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 371 | 651 | 0 |
| MLRVYIYKEGEKPIMHQPGLKGIYASEGWFMKLMEASKKFVTKKPMKAHLFYLPFSSRNLEEELYVPNSHSSKNLVEYLENYLDIIVTTYPFWNRTAGVD HFLVACHDWAPFETKQLMHNCIRALCNADVKEGFVFGKDVSLPETNVPVPKNPLRDLGGKPPSQRSILAFFAGKMHGYLRPILLKHWGDKDPDMKIFGRM PKVRGKMKYSQYMKSSKYCICPRGYEVNSPRIVEAIMYECVPVIISDNYVPPFFEVLNWETFAVFIVEKDIPNLKNILLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 700 Download |
| MGQEFRFRFP METQRLLCLV VMMFVLIITF QHLELPSGNI FSFISSVHTD QVEENGNLFT 60 DDVLSKSETV SNMTQLNGFN STDTDHADER AETYGKEKDT DVNNGLVSEA SAVSKNSFGT 120 DNHNKESSLQ QTQQIFSQEN LSYPLENNTS SDVDNHDKVP SFEQLGQPNV HSTVDNVSNS 180 GFNSGSDVRE QSILKENSSF SCENTGTSNS SIESIVPILP PADSTPNVTF PRNVEPNVVP 240 YVARVDHNAS ALDKDVKSNM VNHGKSGKLQ NNIAAFHDNS SMTTITKEKK KPEMQASGVM 300 SVSEMNSLLL QSWSSPKFMR PQWASAVDQE LLLAKSQIEN APIVENDQIL YSPLYWNISM 360 FKRSYELMEE MLRVYIYKEG EKPIMHQPGL KGIYASEGWF MKLMEASKKF VTKKPMKAHL 420 FYLPFSSRNL EEELYVPNSH SSKNLVEYLE NYLDIIVTTY PFWNRTAGVD HFLVACHDWA 480 PFETKQLMHN CIRALCNADV KEGFVFGKDV SLPETNVPVP KNPLRDLGGK PPSQRSILAF 540 FAGKMHGYLR PILLKHWGDK DPDMKIFGRM PKVRGKMKYS QYMKSSKYCI CPRGYEVNSP 600 RIVEAIMYEC VPVIISDNYV PPFFEVLNWE TFAVFIVEKD IPNLKNILLS IPEERYREMQ 660 MRVKKVQLHF LWHSRPVKYD LFHMILHSVW YNRVLQMQP* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-62 | 372 | 651 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_195005.1 | 0 | 289 | 697 | 184 | 593 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002281263.1 | 0 | 1 | 698 | 1 | 667 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309547.1 | 0 | 233 | 699 | 2 | 470 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002324801.1 | 0 | 305 | 699 | 1 | 397 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002516499.1 | 0 | 1 | 699 | 1 | 600 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
