Basic Information | |
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Species | Manihot esculenta |
Cazyme ID | cassava4.1_021548m |
Family | GT47 |
Protein Properties | Length: 569 Molecular Weight: 65907.2 Isoelectric Point: 6.8207 |
Chromosome | Chromosome/Scaffold: 11519 Start: 4169 End: 5875 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 140 | 484 | 0 |
GRYVYIHHIPSRFNQDLLENCGSITAGTEHNMCPYLVNSALGHEVENSQAILSNKSWHSTNQFLLEVIFHFRMKKYKCLTNDSSLASAIYVPFYAGIDIS RYLWHFNISVRDQSAFELVRWLVEKPEWKKMFGRDHFFVAGRIAWDFRRQTDNESDWGSKLMFLPESNNMSMLAIESSSWKNDYAIPYPTCFHPSKESEV FQWQDKMRRQTRPFLFSFAGAPRPDLQDSIRSKIIEECLASKDLCKLLVCDYGVNGAINCDNPVNVMKLFQNSVFCLQPPGDSYTRRSIFDSILAGCIPV FFNPGTAYAQYKWHLPKNYSKYSVYIPVEDVEDWRAGINQTLLRI |
Full Sequence |
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Protein Sequence Length: 569 Download |
MENPITRNCC NHQLWLVILI SFVLCFVLFG FDYSALIGIQ ERVTVPFANY ENSISTHKSK 60 SPQLPEILNQ TSIAPIKADD LREDNVQQKL KADDPREDNV QQKLKADDLR EENVQKKPVK 120 ADDLREDNVQ QKPVKDFCLG RYVYIHHIPS RFNQDLLENC GSITAGTEHN MCPYLVNSAL 180 GHEVENSQAI LSNKSWHSTN QFLLEVIFHF RMKKYKCLTN DSSLASAIYV PFYAGIDISR 240 YLWHFNISVR DQSAFELVRW LVEKPEWKKM FGRDHFFVAG RIAWDFRRQT DNESDWGSKL 300 MFLPESNNMS MLAIESSSWK NDYAIPYPTC FHPSKESEVF QWQDKMRRQT RPFLFSFAGA 360 PRPDLQDSIR SKIIEECLAS KDLCKLLVCD YGVNGAINCD NPVNVMKLFQ NSVFCLQPPG 420 DSYTRRSIFD SILAGCIPVF FNPGTAYAQY KWHLPKNYSK YSVYIPVEDV EDWRAGINQT 480 LLRIPENRVL AMREEVIKII PRIIYADPRS RMETIEDAFD LAVKGILERI ERVRKVLREG 540 KDPSIGFAEE DHYRFTYSGY VGETLNRI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-66 | 138 | 470 | 347 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193135.2 | 0 | 14 | 560 | 31 | 514 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300146.1 | 0 | 1 | 564 | 7 | 519 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 129 | 559 | 41 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518609.1 | 0 | 127 | 559 | 65 | 493 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 1 | 564 | 1 | 528 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |