| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_022588m |
| Family | GH89 |
| Protein Properties | Length: 504 Molecular Weight: 56964.7 Isoelectric Point: 6.3534 |
| Chromosome | Chromosome/Scaffold: 04083 Start: 443366 End: 448593 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH89 | 97 | 503 | 0 |
| PEIIISGVTGVEVLAGLHWYLKYWCGSHISWEKTGGAQLNSIPDLGFLPRVQVSGISVQRPIPWNYYQNAVTSSYTFAWWDWERWEKEIDWMALHGINLP LAFTGQEAIWQKVFKKFNISKVELDDFFGGPAFLAWSRMGNLHRWGGPLPQSWLDQQLILQKKILTRMYELGMNPVLPAFSGNVPAALANIFPSAKITRL GNWFSVKSDLRWCCTYLLDATDPLFIEIGRAFIEQQIKEYGRISHIYNCDTFDENTPPVDDPDYISALGAAVFKGMQSGDNDAVWLMQGWLFSYDPFWRP LQMKALLHSVPLGRLVVLDLFAEVKPIWITSEQFYGVPYIWCMLHNFAGNIEMYGILDSIASGPVEARASENSTMVGVGMSMEGIEQNPVIYDLMSEMAF QRKKVDV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 504 Download |
| MGSLFPAISI VFLVFSIFSA VHSSTIGVDY ISRLLGIQER ERAPPSVQLA AARGVLRRLL 60 PSHSSAFEFR IVSKEQCGGE SCFIIKNHPS YTRPGTPEII ISGVTGVEVL AGLHWYLKYW 120 CGSHISWEKT GGAQLNSIPD LGFLPRVQVS GISVQRPIPW NYYQNAVTSS YTFAWWDWER 180 WEKEIDWMAL HGINLPLAFT GQEAIWQKVF KKFNISKVEL DDFFGGPAFL AWSRMGNLHR 240 WGGPLPQSWL DQQLILQKKI LTRMYELGMN PVLPAFSGNV PAALANIFPS AKITRLGNWF 300 SVKSDLRWCC TYLLDATDPL FIEIGRAFIE QQIKEYGRIS HIYNCDTFDE NTPPVDDPDY 360 ISALGAAVFK GMQSGDNDAV WLMQGWLFSY DPFWRPLQMK ALLHSVPLGR LVVLDLFAEV 420 KPIWITSEQF YGVPYIWCML HNFAGNIEMY GILDSIASGP VEARASENST MVGVGMSMEG 480 IEQNPVIYDL MSEMAFQRKK VDVK |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12971 | NAGLU_N | 2.0e-15 | 61 | 147 | 87 | + Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This N-terminal domain has an alpha-beta fold. | ||
| pfam05089 | NAGLU | 0 | 162 | 498 | 337 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI15090.1 | 0 | 1 | 504 | 1 | 537 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC78143.1 | 0 | 19 | 504 | 21 | 506 | hypothetical protein OsI_17702 [Oryza sativa Indica Group] |
| RefSeq | XP_002280399.1 | 0 | 1 | 504 | 1 | 504 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318632.1 | 0 | 22 | 504 | 25 | 507 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511461.1 | 0 | 1 | 504 | 1 | 503 | alpha-n-acetylglucosaminidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 55 | 504 | 178 | 601 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 2vcb_A | 0 | 55 | 504 | 178 | 601 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 2vca_A | 0 | 55 | 504 | 178 | 601 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 2vc9_A | 0 | 55 | 504 | 178 | 601 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 55 | 504 | 201 | 624 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
