| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_023143m |
| Family | GT47 |
| Protein Properties | Length: 433 Molecular Weight: 50305.8 Isoelectric Point: 8.2984 |
| Chromosome | Chromosome/Scaffold: 03614 Start: 3601645 End: 3603898 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 53 | 366 | 0 |
| LKVYMYNLPRRFNVGMMDHRNDDDNPPVTAENFPRWPKNSGVRKQHSVEYWLMASLLYEGGGEEREAVRVLDPEKADAFFVPFFSSLSFNTHGHTMTDPE TEIDRQLQVDVIEMLYKSKYWQKSGGRDHVIPMTHPNAFRFLRQQLNASILIVADFGRYPKSMSTLRKDVVAPYVHVVDSFTDDELPDPFESRTTLLFFR GNTVRKDEGKVRAKLEKILAGYGDVHFERSKPTTETIKASTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDQIELPYEDEIDYSQFSVFFSIN EAIQPGYMVDQLRQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 433 Download |
| MYGKLILSMV FIFLLLFSYS IFIGTIDIRS YFFPILQQSP AVAPSVCSHG PPLKVYMYNL 60 PRRFNVGMMD HRNDDDNPPV TAENFPRWPK NSGVRKQHSV EYWLMASLLY EGGGEEREAV 120 RVLDPEKADA FFVPFFSSLS FNTHGHTMTD PETEIDRQLQ VDVIEMLYKS KYWQKSGGRD 180 HVIPMTHPNA FRFLRQQLNA SILIVADFGR YPKSMSTLRK DVVAPYVHVV DSFTDDELPD 240 PFESRTTLLF FRGNTVRKDE GKVRAKLEKI LAGYGDVHFE RSKPTTETIK ASTEGMRSSK 300 FCLHPAGDTP SSCRLFDAIV SHCVPVIVSD QIELPYEDEI DYSQFSVFFS INEAIQPGYM 360 VDQLRQIPKE RWIKMWKLLK NISHHFEFQY PPEKEDAVDM IWRQVKYKLP AVQLAVHRSR 420 RLKIPDWWQR RR* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-73 | 49 | 356 | 316 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18793.1 | 0 | 1 | 409 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
| RefSeq | NP_176908.2 | 0 | 1 | 428 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002272591.1 | 0 | 27 | 432 | 27 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311068.1 | 0 | 52 | 428 | 1 | 380 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002512333.1 | 0 | 1 | 431 | 1 | 434 | catalytic, putative [Ricinus communis] |
