| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_023212m |
| Family | GT47 |
| Protein Properties | Length: 462 Molecular Weight: 52835.2 Isoelectric Point: 8.4685 |
| Chromosome | Chromosome/Scaffold: 03542 Start: 116259 End: 117644 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 80 | 413 | 0 |
| SLFVYQLPQEFNLGLLRDCTHLNVYTDMCPHVANHGLGQPLATSGSWFSTHQFLAEMIFHARLENHPCRTWDPNVANLFYVPFYGGLHASSKFREANQTA RDELAVRLVEFLQMQPWWRRHDGKDHFLALGRTAWDFMRNANGGPDFGANCLLDLPPVKNMSVLTVERQPWQGQNQYGVPYPSYFHPSSVVQMHAWQQKM IRAERNHLFSFIGGPRKGVDKAAVRDELIKQCNESTQCKLLKCGRNSDSKCYEPLEVLKVLSQSHFCLQAAGDSFTRRSTFDSVLAGCIPVFFSRHTAYT QYGWYFPANESEYSVYIDESEIEKKSIEEELSKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 462 Download |
| KPSVPTPWKD QNKGNNFSKT KETHYYYHKL TFRYILLLIF LSSCFLFLVA SFCFSSTNHT 60 HLRFPVISTT AAGNCPGNLS LFVYQLPQEF NLGLLRDCTH LNVYTDMCPH VANHGLGQPL 120 ATSGSWFSTH QFLAEMIFHA RLENHPCRTW DPNVANLFYV PFYGGLHASS KFREANQTAR 180 DELAVRLVEF LQMQPWWRRH DGKDHFLALG RTAWDFMRNA NGGPDFGANC LLDLPPVKNM 240 SVLTVERQPW QGQNQYGVPY PSYFHPSSVV QMHAWQQKMI RAERNHLFSF IGGPRKGVDK 300 AAVRDELIKQ CNESTQCKLL KCGRNSDSKC YEPLEVLKVL SQSHFCLQAA GDSFTRRSTF 360 DSVLAGCIPV FFSRHTAYTQ YGWYFPANES EYSVYIDESE IEKKSIEEEL SKISSDRAER 420 MRRKIIEIMP TITYAHPNSS RVGFEDAVDV ALAALLKLKH K* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-58 | 79 | 397 | 333 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC42883.1 | 0 | 7 | 457 | 14 | 445 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_177014.1 | 0 | 7 | 457 | 14 | 445 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270383.1 | 0 | 81 | 455 | 125 | 495 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300452.1 | 0 | 75 | 455 | 1 | 391 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002336132.1 | 0 | 69 | 455 | 16 | 412 | predicted protein [Populus trichocarpa] |
