| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_023849m |
| Family | GT47 |
| Protein Properties | Length: 365 Molecular Weight: 42271.7 Isoelectric Point: 10.024 |
| Chromosome | Chromosome/Scaffold: 05005 Start: 297750 End: 299117 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 62 | 289 | 6.7e-37 |
| KRFKVWTYKEGERPLAHEGPLNGVYSIEGHFISEIESDKSPFKAQVPGEACVFFLPLSVTSIGQYIYLPIRTMADYSRDRLRRVVTDYTGVIANKYPYWN RMTTTSRHQAELELFQYVVYFQAPDASLANPEIFKNFIRILCNANISEGFKLKRDIPIPEIFTTLEGLNPTNYGQGPKNRTILAFFEGRAHGFIREMLFK HWKNKDSEVVVRENFPEGLGYRKSMGRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 365 Download |
| KKIRSSLEKI EEGLAKARAA IAEAIRSRNC TSSENNNDTF IPRGSVYLNP LAFHQSHIEM 60 VKRFKVWTYK EGERPLAHEG PLNGVYSIEG HFISEIESDK SPFKAQVPGE ACVFFLPLSV 120 TSIGQYIYLP IRTMADYSRD RLRRVVTDYT GVIANKYPYW NRMTTTSRHQ AELELFQYVV 180 YFQAPDASLA NPEIFKNFIR ILCNANISEG FKLKRDIPIP EIFTTLEGLN PTNYGQGPKN 240 RTILAFFEGR AHGFIREMLF KHWKNKDSEV VVRENFPEGL GYRKSMGRSN DVLNWSKFSI 300 EIPVEKIPEI KSILKGISNE KYLMMYRRVK QVERHFVLNR PAKPFDVTYM LLHSLWLRRL 360 NFKA* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-14 | 60 | 289 | 249 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABP03872.1 | 0 | 1 | 363 | 73 | 464 | Exostosin-like [Medicago truncatula] |
| GenBank | ABP03873.1 | 0 | 1 | 363 | 231 | 612 | Exostosin-like [Medicago truncatula] |
| EMBL | CBI25537.1 | 0 | 2 | 362 | 83 | 473 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263848.1 | 0 | 2 | 362 | 2 | 392 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002324623.1 | 0 | 60 | 363 | 1 | 334 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| JK524792 | 250 | 44 | 293 | 0 |
| EC939466 | 299 | 2 | 298 | 0 |
| JG591774 | 221 | 2 | 222 | 0 |
| DN961964 | 221 | 52 | 269 | 0 |
| DW137347 | 254 | 6 | 259 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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