| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_024144m |
| Family | GT47 |
| Protein Properties | Length: 404 Molecular Weight: 45882 Isoelectric Point: 6.8935 |
| Chromosome | Chromosome/Scaffold: 01701 Start: 660394 End: 663998 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 60 | 356 | 0 |
| RLKVFVYELPSKYNKKILQKDPRCLTHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRIMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYLEVKAIERGILHLLQRATLVQTFGQRNHVCLKEEGSITVPPYAPPQKMQAHLIPEKTPRSIFVYFRGLFYDVGNDPEGGYYARG ARAAVWENFKDNPLFDISTEHPTTYYEDMQRAVFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEEIGVFVDEKDVPNLDTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 404 Download |
| MLRNTEGTGK MDIWKWVFVG ILCYAAFAST VGAVKLSRSQ PTERISGSAG DVLEDDPVGR 60 LKVFVYELPS KYNKKILQKD PRCLTHMFAA EIFMHRFLLS SPVRTLNPEE ADWFYTPVYT 120 TCDLTPNGLP LPFKSPRIMR SAIQLISSNW PYWNRTEGAD HFFVVPHDFG ACFHYLEVKA 180 IERGILHLLQ RATLVQTFGQ RNHVCLKEEG SITVPPYAPP QKMQAHLIPE KTPRSIFVYF 240 RGLFYDVGND PEGGYYARGA RAAVWENFKD NPLFDISTEH PTTYYEDMQR AVFCLCPLGW 300 APWSPRLVEA VIFGCIPVII ADDIVLPFAD AIPWEEIGVF VDEKDVPNLD TILTSIPPEV 360 ILRKQRLLAN PSMKQAMLFP QPAQPGDAFH QVLNGLARKL PHDR 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-81 | 60 | 356 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM64940.1 | 0 | 11 | 404 | 1 | 391 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_568941.1 | 0 | 11 | 404 | 1 | 391 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002284685.1 | 0 | 11 | 404 | 1 | 392 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318180.1 | 0 | 11 | 404 | 1 | 393 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 11 | 404 | 1 | 393 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
