| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_025515m |
| Family | GT47 |
| Protein Properties | Length: 483 Molecular Weight: 55963.8 Isoelectric Point: 6.9654 |
| Chromosome | Chromosome/Scaffold: 06140 Start: 12149 End: 13597 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 62 | 394 | 0 |
| SCSGRYIYVHRLPPRFNDHVLQNCTSLYRWYDMCPFVGNSGFGMQLGKSWFATNQFLLEVIFRNRMNQYDCLTDDSSLASAIFVPSYCGLDLGRYLWDYN ASVRDTLSLDLVRWLAKQPQWKRMSGRDHFFVAGRISWDFRRDINNDEGWGSVLMSLPESMNMTMLTIESNSWTNEFAIPYPTHFHPSTDSEVIQWQETV RKHKRKYLFSFAGAPRPLLSDSIRSQIIDQCVASERLCKLLDCNSGPNKCDSPVEVLKLFQDSIFCLQPPGDSYTRRSTFDSILTGCIPVFFHPGSAYAQ YFWYFPKNYTKYSVFIPGYQVKNASISINETLL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 483 Download |
| MEKSIIALNR YWFVIFVVSF LFFLFLYSFD YNPAFLSNNS LFNTRRKPNH DPKSNETHPI 60 DSCSGRYIYV HRLPPRFNDH VLQNCTSLYR WYDMCPFVGN SGFGMQLGKS WFATNQFLLE 120 VIFRNRMNQY DCLTDDSSLA SAIFVPSYCG LDLGRYLWDY NASVRDTLSL DLVRWLAKQP 180 QWKRMSGRDH FFVAGRISWD FRRDINNDEG WGSVLMSLPE SMNMTMLTIE SNSWTNEFAI 240 PYPTHFHPST DSEVIQWQET VRKHKRKYLF SFAGAPRPLL SDSIRSQIID QCVASERLCK 300 LLDCNSGPNK CDSPVEVLKL FQDSIFCLQP PGDSYTRRST FDSILTGCIP VFFHPGSAYA 360 QYFWYFPKNY TKYSVFIPGY QVKNASISIN ETLLQFSDEQ IMDMREEVIK LIPKVIYADP 420 SSKLETIEDA FDIAVKGVLE RVEKVRREIK EGRDPGIAFA VGNSWKLKLS GTGLENDLDF 480 FF* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-65 | 62 | 396 | 349 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002321098.1 | 0 | 59 | 481 | 46 | 477 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002518604.1 | 0 | 34 | 482 | 53 | 457 | catalytic, putative [Ricinus communis] |
| RefSeq | XP_002518606.1 | 0 | 34 | 481 | 53 | 498 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| RefSeq | XP_002518609.1 | 0 | 1 | 481 | 1 | 501 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| RefSeq | XP_002532518.1 | 0 | 1 | 471 | 1 | 523 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
