| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_025682m |
| Family | GT47 |
| Protein Properties | Length: 290 Molecular Weight: 32527.2 Isoelectric Point: 8.0011 |
| Chromosome | Chromosome/Scaffold: 05214 Start: 1246721 End: 1248276 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 181 | 289 | 2.7e-30 |
| KLFKIYVYEEGEPPLFHEGPCKSIYSTEGRFIHEMERGNFFRTRNPNEALVYFLPFSVVRMVQYLYVPGAHEIHAIGRAVVDYINIISDKHPFWNRSLGA DHFMLSCHD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 290 Download |
| MSPPNKKLSS SSSSLSLGSP SFLVLIVAVP LVVISMVVFL LIPQSFSWSS LPSRATRRVG 60 ICGSYPCASF PLEEEAPGNF SIFNSSESLI AKELIQSGQA QETLSLKESD EVGVNATAKV 120 IKRYSSLAKV EASLAKARSA IREAARVRNL TSVHEDPDYV PRGPIYRNAN SFHRSYLEME 180 KLFKIYVYEE GEPPLFHEGP CKSIYSTEGR FIHEMERGNF FRTRNPNEAL VYFLPFSVVR 240 MVQYLYVPGA HEIHAIGRAV VDYINIISDK HPFWNRSLGA DHFMLSCHDW 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-11 | 179 | 290 | 119 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC83915.1 | 0 | 122 | 290 | 211 | 379 | limonene cyclase like protein [Oryza sativa Japonica Group] |
| EMBL | CBI28483.1 | 0 | 122 | 290 | 28 | 196 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001059081.1 | 0 | 122 | 290 | 211 | 379 | Os07g0188700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002459470.1 | 0 | 109 | 290 | 164 | 345 | hypothetical protein SORBIDRAFT_02g005180 [Sorghum bicolor] |
| RefSeq | XP_002524591.1 | 0 | 1 | 290 | 1 | 284 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
